32560-70-6

Basic information

• Product Name: 1-(4-ethoxy-3-methoxyphenyl)propan-2-amine
• Synonyms: 1-(4-ethoxy-3-methoxyphenyl)propan-2-amine
• CAS NO: 32560-70-6
• Molecular Weight: 209.288
• Mol File: 32560-70-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-ethoxy-3-methoxyphenyl)propan-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-ethoxy-3-methoxyphenyl)propan-2-amine(32560-70-6)
• EPA Substance Registry System: 1-(4-ethoxy-3-methoxyphenyl)propan-2-amine(32560-70-6)

Safety Data

• Hazardous Substances Data: 32560-70-6(Hazardous Substances Data)

Upstream product

• 126278-69-1 1-(4-ethoxy-3-methoxyphenyl)propan-2-one 
• 120-25-2 4-ethoxy-3-methoxybenzaldehyde 
• 121-33-5 vanillin 

Downstream Products

• 126278-69-1 1-(4-ethoxy-3-methoxyphenyl)propan-2-one 

Relevant articles and documents

Transaminase-mediated synthesis of enantiopure drug-like 1-(3′,4′-disubstituted phenyl)propan-2-amines

Transaminases (TAs) offer an environmentally and economically attractive method for the direct synthesis of pharmaceutically relevant disubstituted 1-phenylpropan-2-amine derivatives starting from prochiral ketones. In this work, we report the application of immobilised whole-cell biocatalysts with (R)-transaminase activity for the synthesis of novel disubstituted 1-phenylpropan-2-amines. After optimisation of the asymmetric synthesis, the (R)-enantiomers could be produced with 88-89% conversion and >99% ee, while the (S)-enantiomers could be selectively obtained as the unreacted fraction of the corresponding racemic amines in kinetic resolution with >48% conversion and >95% ee. This journal is