32565-17-6Relevant articles and documents
New One-Pot Synthesis of Polysubstituted Benzofurans and Benzo-1,4-dioxines
Sakhabutdinova,Raskil’dina,Zlotskii,Sultanova
, p. 233 - 236 (2018/11/21)
It has been revealed that the copper(II) triflate catalyzed reaction of ethyl-2-diazo-3-oxobutanoate with phenols followed by cyclization of the intermediate enol in the presence of polyphosphoric acid is a simple and efficient method of synthesis of polysubstituted benzofurans. The use of pyrocatechol leads to the corresponding substituted 1,4-benzodioxine-2-carboxylates as major products.