32804-79-8

Basic information

• Product Name: 2-METHOXYISOPROPYL CYANOACETATE
• Synonyms: 2-MIPCA;2-METHOXYISOPROPYL CYANOACETATE;2-methoxy-1-methylethyl cyanoacetate;2-METHOXY-1-METHYLETHYL CYANOACETATE, 96 %;Acetic acid, cyano-, 2-methoxy-1-methylethyl ester;Cyanoacetic acid 2-methoxyisopropyl ester
• CAS NO: 32804-79-8
• Molecular Formula: C₇H₁₁NO₃
• Molecular Weight: 157.17
• Mol File: 32804-79-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 103-105 °C/2 mmHg(lit.)
• Flash Point: 63 °C
• Appearance: /
• Density: 1.03 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00744mmHg at 25°C
• Refractive Index: n20/D 1.431(lit.)
• CAS DataBase Reference: 2-METHOXYISOPROPYL CYANOACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXYISOPROPYL CYANOACETATE(32804-79-8)
• EPA Substance Registry System: 2-METHOXYISOPROPYL CYANOACETATE(32804-79-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26-36
• Hazardous Substances Data: 32804-79-8(Hazardous Substances Data)

Usage

General Description

2-Methoxyisopropyl cyanoacetate is a chemical compound with the molecular formula C7H11NO3. It is a colorless liquid with a faint odor that is used in the pharmaceutical and chemical industries as a building block for the synthesis of various compounds. This chemical is commonly used as a reagent in the production of pharmaceuticals and agrochemicals. It is also a key intermediate in the manufacture of fragrances, flavors, and other fine chemicals. 2-Methoxyisopropyl cyanoacetate has a versatile range of applications in various industries due to its ability to react with a wide variety of other chemicals and its role as a precursor in the synthesis of complex organic molecules.

InChI:InChI=1/C7H11NO3/c1-6(5-10-2)11-7(9)3-4-8/h6H,3,5H2,1-2H3

Upstream product

• 107-98-2 1-methoxy-2-propanol 
• 372-09-8 cyanoacetic acid 
• 151-50-8 potassium cyanide 

Downstream Products

• 313486-17-8 (+/-)1-methoxy-2-propyl benzylidenecyanoacetate 
• 27279-62-5 2-cyano-acrylic acid-(β-methoxy-isopropyl ester) 

Relevant articles and documents

A new class of small molecule RNA polymerase inhibitors with activity against Rifampicin-resistant Staphylococcus aureus1

The RNA polymerase holoenzyme is a proven target for antibacterial agents. A high-throughput screening program based on this enzyme from Staphylococcus aureus had previously identified a 2-ureidothiophene-3-carboxylate as a low micromolar inhibitor. An investigation of the relationships between the structures of this class of compounds and their inhibitory- and antibacterial activities is described here, leading to a set of potent RNA polymerase inhibitors with antibacterial activity. Characterization of this bioactivity, including studies of the mechanism of action, is provided, highlighting the power of the reverse chemical genetics approach in providing tools to inhibit the bacterial RNA polymerase.