329015-81-8Relevant articles and documents
seco-Cyclothialidines: New concise synthesis, inhibitory activity toward bacterial and human DNA topoisomerases, and antibacterial properties
Rudolph,Theis,Hanke,Endermann,Johannsen,Geschke
, p. 619 - 626 (2007/10/03)
seco-Cyclothialidines are a promising class of bacterial DNA gyrase B subunit inhibitors. A new seco-cyclothialidine derivative containing a dioxazine moiety, BAY 50-7952, was synthesized through a new concise pathway. One key step of the synthesis is the