32953-62-1

Basic information

• Product Name: 2,2-dimethyl-5-(2-oxo-1,3-oxathiolan-5-yl)tetrahydrofuro[2,3-d][1,3]dioxol-6-yl acetate (non-preferred name)
• CAS NO: 32953-62-1
• Molecular Formula: C₁₂H₁₆O₇S
• Molecular Weight: 304.3162
• Mol File: 32953-62-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 389.9°C at 760 mmHg
• Flash Point: 188.1°C
• Density: 1.42g/cm³
• Vapor Pressure: 2.76E-06mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: 2,2-dimethyl-5-(2-oxo-1,3-oxathiolan-5-yl)tetrahydrofuro[2,3-d][1,3]dioxol-6-yl acetate (non-preferred name)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethyl-5-(2-oxo-1,3-oxathiolan-5-yl)tetrahydrofuro[2,3-d][1,3]dioxol-6-yl acetate (non-preferred name)(32953-62-1)
• EPA Substance Registry System: 2,2-dimethyl-5-(2-oxo-1,3-oxathiolan-5-yl)tetrahydrofuro[2,3-d][1,3]dioxol-6-yl acetate (non-preferred name)(32953-62-1)

Safety Data

• Hazardous Substances Data: 32953-62-1(Hazardous Substances Data)

Usage

General Description

The chemical "2,2-dimethyl-5-(2-oxo-1,3-oxathiolan-5-yl)tetrahydrofuro[2,3-d][1,3]dioxol-6-yl acetate" is a complex organic compound with a non-preferred name. It is an acetate derivative with a tetrahydrofuran ring and a dioxolane ring, along with a 1,3-oxathiolane-2-one moiety. This chemical is a synthetic compound and is not commonly known by a specific common name. It may be used in laboratory research or industrial processes, but its potential uses and applications are not readily available. Due to its complex structure and lack of a common name, it may not be widely recognized or utilized in commercial or scientific settings.

Upstream product

• 2946-02-3 1,2-O-isopropylidene-5,6-O-thiocarbonyl-α-D-glucofuranose O-acetate 
• 18549-40-1 1,2-O-isopropylidene-α-D-glucofuranose 
• 2816-87-7 1,2-di-O-isopropylidene-5,6-O-thiocarbonyl-α-D-glucofuranose 

Relevant articles and documents

Stereoselective synthesis of new glycooxathiecinone using vic-cyclic thionocarbonate haloalkylation and ring closing metathesis as key steps

Herein, we describe the first glycoconjugate macrocyclic thiolcarbonate namely (Z)-10(S)-[3′-O-acetyl-1′,2′-O-isopropylidene-4′-deoxy-d-erythrofuranose]-4,7,9-trihydro-10H-8-thia-1,3-oxathiecin-2-one (17a) using a strategy based on two key steps synthesis: (i) a haloalkylation of vic-diol via their cyclic thionocarbonate derivatives; (ii) a macrocyclisation using ring closing metathesis reaction. Detailed here is a newly developed extension of vic-diol halogenation via the cyclic thionocarbonate function but using a range of alkyl halides other than the customarily used MeI. For example, with 1,2-O-isopropylidene-5,6-O-thionocarbonate-d-glucose (1) and allyl bromide, the 5-allylthiolcarbonate-6-bromo-6-deoxy-d-glucose derivative 6 was obtained in good yield. The later submitted to 6-allythioetherification and ring closing metathesis (RCM) with Grubbs second generation gave stereoselectively the target oxathiecinone 17a in 75% yield for the RCM step.

TRIALKYLTIN RADICAL USED TO CATALYZE THE O,S-REARRANGEMENT OF CYCLIC THIONOCARBONATES. A NEW ENTRY TO THIO-SUGARS

The cyclic thionocarbonates give O,S-rearrangement products, the thiolcabonates, in appreciable yields, when treated with a catalytic amount of tributyltin hydride and α,α-azobisisobutyronitrile.This reaction opens a new route to regioselective preparatio