3297-64-1

Basic information

• Product Name: 2-Quinolinecarboxylic acid, 1-oxide
• CAS NO: 3297-64-1
• Molecular Formula: C10H7NO3
• Molecular Weight: 189.17
• Mol File: 3297-64-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Quinolinecarboxylic acid, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Quinolinecarboxylic acid, 1-oxide(3297-64-1)
• EPA Substance Registry System: 2-Quinolinecarboxylic acid, 1-oxide(3297-64-1)

Safety Data

• Hazardous Substances Data: 3297-64-1(Hazardous Substances Data)

Usage

General Description

2-Quinolinecarboxylic acid, 1-oxide is a heterocyclic compound with a molecular formula C10H7NO2. It is a derivative of quinoline containing a carboxylic acid group and an oxygen atom attached to the nitrogen atom. This chemical is used in the synthesis of various pharmaceuticals and agrochemicals due to its diverse biological activities. It exhibits antimicrobial, antifungal, and antiviral properties making it a potential candidate for drug development. Additionally, it has been studied for its potential use as a corrosion inhibitor in various industrial applications. Overall, 2-Quinolinecarboxylic acid, 1-oxide has a wide range of potential applications and is a versatile compound in the field of chemistry and pharmacology.

Upstream product

• 95113-35-2 1,3-diphenyl-1-(2-quinolyl)acetone 

Downstream Products

• 1613316-52-1 2-(4-cyanophenyl)quinoline N-oxide 
• 1262240-94-7 2-(4-chlorophenyl)quinoline N-oxide 
• 1613316-51-0 2-(4-(trifluoromethyl)phenyl)quinoline N-oxide 
• 1613316-50-9 2-(3,4-dimethoxyphenyl)quinoline N-oxide 
• 36710-31-3 2-(4-methoxylphenyl)quinoline N-oxide 
• 1127561-54-9 2-(3-methoxyphenyl)quinoline N-oxide 
• 1127561-50-5 2-(2-methylphenyl)quinoline N-oxide 
• 5659-33-6 2-phenylquinoline 1-oxide 
• 74831-33-7 2-(4-methylphenyl)quinoline N-oxide 
• 93-10-7 quinoline-2-carboxylic acid 

Relevant articles and documents

Studies on Tertiary Amine Oxides. LXXX.1) Reaction of Quinoline 1-oxide with Phenylacetic Anhydride

Treatment of quinoline 1-oxide (1) with phenylacetic acid and acetic anhydride in boiling benzene for 10 h gave benzaldehyde (2), quinoline (3), 2-benzylquinoline (4), 2-benzoylquinoline (5), phenyl-di(2-quinolyl)carbinol (6), di(2-quinolyl) ketone (7), and N-(2-quinolyl)-2-benzylidene-1,2-dihydroquinoline (8) in small yields.The reaction of 1 with phenylacetic anhydride in boiling benzene for 10 h afforded 1,3-diphenyl-1-(2-quinolyl)acetone (9) and dibenzyl ketone (10) together with small amounts of 2, 3, and 5.Further, it was found that phenylacetic anhydrideundergoes decarboxylative coupling upon heating with tertiary amines to give 10.The mechamisms of these reactions are discussed. Keywords --- nucleophilic reaction; oxidative decarboxylation; decarboxylative coupling; benzaldehyde; 2-benzylquinoline; phenyl-di(2-quinolyl)carbinol; N-(2-quinolyl)-2-benzylidene-1,2-dihydroquinoline; 1,3-diphenyl-1-(2-quinolyl)acetone; dibenzyl ketone