33007-09-9

Basic information

• Product Name: FURO[3,2-C]PYRIDIN-4-AMINE
• Synonyms: FURO[3,2-C]PYRIDIN-4-AMINE;4-amino-furo[3,2-c]pyridine
• CAS NO: 33007-09-9
• Molecular Formula: C₇H₆N₂O
• Molecular Weight: 134.14
• Mol File: 33007-09-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 285.588 °C at 760 mmHg
• Flash Point: 126.519 °C
• Appearance: /
• Density: 1.317 g/cm³
• PKA: 6.16±0.30(Predicted)
• CAS DataBase Reference: FURO[3,2-C]PYRIDIN-4-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: FURO[3,2-C]PYRIDIN-4-AMINE(33007-09-9)
• EPA Substance Registry System: FURO[3,2-C]PYRIDIN-4-AMINE(33007-09-9)

Safety Data

• Hazardous Substances Data: 33007-09-9(Hazardous Substances Data)

Usage

General Description

Furo[3,2-c]pyridin-4-amine, also known as acridine, is a chemical compound that belongs to the pyridine class of organic compounds. It is a heterocyclic compound containing a furo group fused to a pyridine ring. Furo[3,2-c]pyridin-4-amine is commonly used in the pharmaceutical industry for the development of potential drug candidates due to its structural and biological activity. It has been studied for its potential antitumor, antiviral, and antimicrobial properties. Additionally, it can be used as a precursor in the synthesis of various organic compounds. Furo[3,2-c]pyridin-4-amine is primarily synthesized through chemical reactions, and its properties and applications continue to be explored in scientific research.

Upstream product

• 31270-80-1 4-chlorofuro[3,2-c]pyridine 
• 33007-15-7 7-hydroxy-6,7-dihydro-5H-furo[3,2-c]pyridin-4-one 
• 26956-43-4 5H-furo[3,2-c]pyridin-4-one 
• 46265-05-8 2-(2-amino-1-hydroxy-ethyl)-furan-3-carboxylic acid ethyl ester 
• 26956-43-4 furo[3,2-c]pyridine-4-ol 
• 33007-16-8 4-hydrazinylfuro[3,2-c]pyridine 

Downstream Products

• 252970-97-1 2-amino-3-(4-amino-furo[3,2-c]pyridin-2-yl)-propionic acid methyl ester 
• 252970-82-4 β-[2-(4-aminofuro[3,2-c]pyridine)]alanine 
• 215453-74-0 N-(2-hydroxymethyl-furo[3,2-c]pyridin-4-yl)-benzamide 
• 252971-09-8 3-(4-amino-furo[3,2-c]pyridin-2-yl)-2-tert-butoxycarbonylamino-propionic acid 
• 252971-51-0 [1-(4-amino-furo[3,2-c]pyridin-2-ylmethyl)-2-(4-methyl-piperidin-1-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester 
• 215453-79-5 3-(4-amino-furo[3,2-c]pyridin-2-yl)-2-(7-methoxy-naphthalene-2-sulfonylamino)-propionic acid methyl ester 
• 215453-75-1 2-(4-benzoylamino-furo[3,2-c]pyridin-2-ylmethyl)-2-tert-butoxycarbonylamino-malonic acid diethyl ester 
• 1309048-45-0 N-{2-(2-cyano-3-oxobut-1-en-1-yl)furo[3,2-c]pyridin-4-yl}benzamide 
• 1309048-23-4 N-{2-[3,5-dicyano-2-(difluoromethyl)-6-methyl-1,4-dihydropyridin-4-yl]furo[3,2-c]pyridin-4-yl}benzamide 
• 1309048-24-5 N-{2-[3,5-dicyano-2-(4-fluorophenyl)-6-methyl-1,4-dihydropyridin-4-yl]furo[3,2-c]pyridin-4-yl}benzamide 
• 1309048-25-6 N-{2-[3,5-dicyano-2-(4-chlorophenyl)-6-methyl-1,4-dihydropyridin-4-yl]furo[3,2-c]pyridin-4-yl}benzamide 
• 1309048-26-7 N-{2-[3,5-dicyano-2,6-dimethyl-1,4-dihydropyridin-4-yl]furo[3,2-c]pyridin-4-yl}benzamide 
• 1309048-27-8 4-(4-aminofuro[3,2-c]pyridin-2-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonitrile 
• 1309048-29-0 N-{2-[3,5-dicyano-2-methyl-6-(trifluoromethyl)-1,4-dihydropyridin-4-yl]furo[3,2-c]pyridin-4-yl}benzamide 

Relevant articles and documents

AMINOPYRIDINE COMPOUNDS AND METHODS FOR THE PREPARATION AND USE THEREOF

The present invention relates generally to therapeutics targeting the bacterium Porphyromonas gingivalis, including its proteases arginine gingipain A/B (Rgp), and their use for the treatment of disorders associated with P. gingivalis infection, including brain disorders such as Alzheimer's disease. In certain embodiments, the invention provides compounds according to Formula I and Formula III, as described herein, and pharmaceutically acceptable salts thereof.

QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic 7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.

QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.