330151-22-9

Basic information

• Product Name: 1,2-O-Isopropylidene-3,5-O-(2-phenylsulfonyl)ethylidene-α-D-xylofuranose
• Synonyms: 1,2-O-Isopropylidene-3,5-O-(2-phenylsulfonyl)ethylidene-α-D-xylofuranose
• CAS NO: 330151-22-9
• Molecular Weight: 356.397
• Mol File: 330151-22-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,2-O-Isopropylidene-3,5-O-(2-phenylsulfonyl)ethylidene-α-D-xylofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-O-Isopropylidene-3,5-O-(2-phenylsulfonyl)ethylidene-α-D-xylofuranose(330151-22-9)
• EPA Substance Registry System: 1,2-O-Isopropylidene-3,5-O-(2-phenylsulfonyl)ethylidene-α-D-xylofuranose(330151-22-9)

Safety Data

• Hazardous Substances Data: 330151-22-9(Hazardous Substances Data)

Upstream product

• 35387-59-8 1,2-Bis(phenylsulfonyl)ethylene 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 20881-04-3 1,2:3,5-di-O-isopropylidene-D-xylofuranose 
• 532-20-7 α-D-xylofuranose 

Downstream Products

• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 943856-01-7 1,2-di-O-acetyl-3,5-O-(2-phenylsulfonyl)ethylidene-D-xylofuranose 
• 943856-04-0 C₂₆H₂₅N₃O₉S 
• 943856-02-8 C₂₀H₂₁N₅O₇S 
• 943856-03-9 C₁₉H₂₀N₂O₉S 
• 1353644-97-9 1,2-O-isopropylidene-5-O-[(E)-2'-(phenylsulfonyl)vinyl]-α-D-xylofuranose 
• 1353644-99-1 5-O-tert-butyldimethylsilyl-1,2-O-isopropylidene-3-O-[(E)-2'-(phenylsulfonyl)vinyl]-α-D-xylofuranose 

Relevant articles and documents

Probing of PSE acetal protection for nucleoside chemistry

The use of phenylsulfonylethylidene (PSE) acetal as a new 3′,5′-bridged protecting group in nucleoside chemistry is reported. The PSE acetal demonstrates to be compatible with Lewis acids used in standard glycosylation reactions. In addition, a selective 2′-O-deacylation from a 3′,5′-O-(phenylsulfonyl)-2′-O-acetyl nucleoside can be achieved, giving access to subsequent chemical modifications in 2′ position. However, the PSE acetal cleavage surprisingly appeared to be purine/pyrimidine base dependent.

Phenylsulfonylethylidene (PSE) acetals as atypical carbohydrate- protective groups

We introduce a new class of arylsulfonylated cyclic acetals derived from carbohydrate structures which are synthesized with high yields under basic conditions. Deprotection methods for such acetals are also investigated. (C) 2000 Elsevier Science Ltd.