33166-49-3

Basic information

• Product Name: 3,3,3-triphenylpropionyl chloride
• Synonyms: 3,3,3-triphenylpropionyl chloride
• CAS NO: 33166-49-3
• Molecular Weight: 320.818
• Mol File: 33166-49-3.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 3,3,3-triphenylpropionyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3,3-triphenylpropionyl chloride(33166-49-3)
• EPA Substance Registry System: 3,3,3-triphenylpropionyl chloride(33166-49-3)

Safety Data

• Hazardous Substances Data: 33166-49-3(Hazardous Substances Data)

Upstream product

• 900-91-4 3,3,3-triphenylpropionic acid 
• 463-51-4 Ketene 
• 76-83-5 trityl chloride 
• 98-95-3 nitrobenzene 
• 7446-70-0 aluminium trichloride 
• 71-43-2 benzene 
• 76-84-6 triphenylmethyl alcohol 

Downstream Products

• 16778-09-9 4,4,4-triphenylbutanoic acid 
• 50354-49-9 3,3,3-triphenylpropionic acid methyl ester 
• 900-91-4 3,3,3-triphenylpropionic acid 
• 55010-17-8 3,3-diphenyl-indan-1-one 
• 13733-56-7 4,4,4-triphenylbutan-2-one 
• 90461-31-7 1,1,1-triphenylpropanal 
• 147355-13-3 3,3,3-triphenylpropionic amide 
• 858446-22-7 3,3,3-triphenyl-propionohydroxamic acid 
• 102592-16-5 2-bromo-3,3,3-triphenyl-propionic acid ethyl ester 
• 1801-42-9 2,3-diphenyl-1H-inden-1-one 

Relevant articles and documents

Molecular and supramolecular helicity induction in trityl group-containing compounds: The case of chiral 3,3,3-triphenylpropionic acid derivatives

The process of dynamic chirality transmission from permanent chirality element to stereodynamic triphenylmethyl group placed in the distance of 4 bonds, has been studied for series of optically active 3,3,3-triphenylpropionic acid derivatives. Structural

Development of a fluorescent cardiomyocyte specific binding probe

Cardiomyocytes are the major component of the heart. Their dysfunction or damage could lead to serious cardiovascular diseases, which have claimed numerous lives around the world. A molecule able to recognize cardiomyocytes would have significant value in diagnosis and treatment. Recently a novel peptide termed myocyte targeting peptide (MTP), with three residues of a non-natural amino acid biphenylalanine (Bip), showed good affinity to cardiomyocytes. Its selectivity towards cardiac tissues was concluded to be due to the ability of Bip to bind cardiac troponin I. With the aim of optimizing the affinity and the specificity towards cardiac myocytes and to better understand structure-activity relationship, a library of MTP derivatives was designed. Exploiting a fluorescent tag, the selectivity of the MTP analogs to myocardium over skeletal and stomach muscle tissues was assayed by fluorescence imaging. Among the tested sequences, the peptide probe Bip2, H-Lys(FITC)-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Ser-Gly-Ser-Bip-Bip-NH2, displayed the best selectivity for cardiomyocytes.

Dual polyrotaxane: One-pot synthesis of topological polymer by using metathesis reaction

The topological polyrotaxane was built from an ammonium salt as an axle component bearing one olefin and one bulky unit at the end of chain and the derivative of dibenzo-24-crown-8 (DB24C8) as a wheel component having one terminal olefin. In this system, two kinds of reactions work at the same time as a driving force of the polymer construction. One is the inclusion reaction between the ammonium salt part of axle and the wheel, another is metathesis reaction between olefins of the axle and olefins of the wheel. Copyright