333795-06-5Relevant articles and documents
USE OF COMPOUNDS HAVING CCR ANTAGONISM
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Page/Page column 86, (2010/02/10)
It is intended to provide preventives/remedies for graft-versus-host disease and/or rejection in organ or bone marrow transplantation, rheumatoid arthritis, autoimmune diseases, allergic diseases, ischemic cerebral cell injury, myocardial infarction, chro
CCR5 antagonists as anti-HIV-1 agents. Part 2: Synthesis and biological evaluation of N-[3-(4-benzylpiperidin-1-yl)propyl]-N,N′- diphenylureas
Imamura, Shinichi,Kurasawa, Osamu,Nara, Yoshi,Ichikawa, Takashi,Nishikawa, Youichi,Iida, Takehiro,Hashiguchi, Shohei,Kanzaki, Naoyuki,Iizawa, Yuji,Baba, Masanori,Sugihara, Yoshihiro
, p. 2295 - 2306 (2007/10/03)
We have previously reported the novel lead compound 1a as a CCR5 antagonist for treatment of HIV-1 infection. SAR studies on incorporating various acyl groups as a replacement for the 5-oxopyrrolidine-3-carbonyl group of the lead structure resulted in the
UREA COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF
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, (2008/06/13)
A compound of the formula: [whereinR1 is a hydrocarbon group which may be substituted;R2 is a cyclic hydrocarbon group which may be substituted or a heterocyclic group which may be substituted;R3 is halogen atoms, a carbam