33509-76-1Relevant articles and documents
Peroxides as "switches" of dialkyl H-phosphonate: Two mild and metal-free methods for preparation of 2-acylbenzothiazoles and dialkyl benzothiazol-2-ylphosphonates
Chen, Xiao-Lan,Li, Xu,Qu, Ling-Bo,Tang, Yu-Chun,Mai, Wen-Peng,Wei, Dong-Hui,Bi, Wen-Zhu,Duan, Li-Kun,Sun, Kai,Chen, Jian-Yu,Ke, Dian-Dian,Zhao, Yu-Fen
, p. 8407 - 8416 (2014)
Two mild and metal-free methods for the preparation of two kinds of important benzothiazole derivatives, 2-acylbenzothiazoles and dialkyl benzothiazol-2-ylphosphonates, respectively, were developed. The dialkyl H-phosphonate (RO)2P(O)H exists i
Chloroacetate-promoted selective oxidation of heterobenzylic methylenes under copper catalysis
Liu, Jianming,Zhang, Xin,Yi, Hong,Liu, Chao,Liu, Ren,Zhang, Heng,Zhuo, Kelei,Lei, Aiwen
supporting information, p. 1261 - 1265 (2015/01/30)
The efficient selective oxidation and functionalization of C-H bonds with molecular oxygen and a copper catalyst to prepare the corresponding ketones was achieved with ethyl chloroacetate as a promoter. In this transformation, various substituted N-heterocyclic compounds were well tolerated. Preliminary mechanistic investigations indicated that organic radical species were involved in the overall process. The N-heterocyclic compounds and ethyl chloroacetate work synergistically to activate C-H bonds in the methylene group, which results in the easy generation of free radical intermediates, thus leading to the corresponding ketones in good yields.
