3352-87-2

Basic information

• Product Name: N,N-Diethyldodecanamide
• Synonyms: Diethyllauramide;n,n-diethyl-dodecanamid;N,N-Diethyllaurylamide;Nopcogen 14-l;nopcogen14-l;N-LAUROYLDIETHYLAMINE;N,N-DIETHYLLAURAMIDE;N,N-DIETHYLDODECANAMIDE
• CAS NO: 3352-87-2
• Molecular Formula: C₁₆H₃₃NO
• Molecular Weight: 255.44
• EINECS: 222-118-3
• Mol File: 3352-87-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: 3-5°C
• Boiling Point: 166-167 °C2 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: Colorless to pale yellow liquid
• Density: 0.847 g/mL at 25 °C(lit.)
• Vapor Pressure: 3.18E-05mmHg at 25°C
• Refractive Index: n20/D 1.454(lit.)
• PKA: -0.43±0.70(Predicted)
• CAS DataBase Reference: N,N-Diethyldodecanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Diethyldodecanamide(3352-87-2)
• EPA Substance Registry System: N,N-Diethyldodecanamide(3352-87-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 2
• RTECS: RB4200000
• TSCA: Yes
• Hazardous Substances Data: 3352-87-2(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR COLORLESS TO LIGHT YELLOW LIQUID

Uses

N,N-Diethyldodecanamide is used as pharmaceutical intermediate.

InChI:InChI=1/C16H33NO/c1-4-7-8-9-10-11-12-13-14-15-16(18)17(5-2)6-3/h4-15H2,1-3H3

Upstream product

• 112-54-9 Dodecanal 
• 2523-98-0 N,N-diethyl thiophosphorodichloridate 
• 143-07-7 lauric acid 
• 112-16-3 n-dodecanoyl chloride 
• 109-89-7 diethylamine 
• 33641-61-1 N,N,N′,N′-tetraethylthionylamide 

Downstream Products

• 35902-57-9 N-n-dodecyl-ethylamine 
• 3007-31-6 N,N-didodecylamine 
• 112-53-8 1-dodecyl alcohol 
• 41903-81-5 hexadecan-5-one 
• 112-54-9 Dodecanal 
• 4271-27-6 diethyllaurylamine 

Relevant articles and documents

A continuous water removal product and production method

The invention relates to a method for continuous water removal production of amide product; first, ammonium salt is produced by pre neutralization reaction of raw material carboxylic acid and amine, the ammonium salt is further dehydrated to obtain amide and by-product water. According to the method, by countercurrent contact recycle gas and raw material amine desorption, carrying, condensation separation, the by-product water is timely moved out of the reaction section, the reaction is promoted, the amine circulation proportion is reduced, and the material loss is reduced. The amide product prepared by the method not only can be used in natural organic carboxylic acids, and is also applicable to synthesized aromatic carboxylic acids, the process is clean and environmentally-friendly; and the product amide is high in purity and free of salt.

An easy access to tertiary amides from aldehydes and N,N- dialkylchlorothiophosphoramidates

A mechanistically unprecedented approach for the formation of tertiary amides from N,N-dialkylchlorothiophosphoramidates and aldehydes has been developed. The reaction occurred via the activation of aldehydes with N,N-dialkylchlorothiophosphoramidates followed by amidation with dialkylamine pendent of the same phosphoramidate.

A convenient method for the synthesis and one-pot reaction of acyl chlorides using a scavenging resin

A simple, efficient and fast method for the preparation of acyl halides from fatty carboxylic acids using a solid phase scavenging approach is presented herein. The title compounds can then be isolated, used as a solution or react in one-pot to form esters and amides with good to excellent yields.