336619-72-8Relevant articles and documents
Optimization of the central linker of dicationic bis-benzimidazole anti-MRSA and anti-VRE agents
Hu, Laixing,Kully, Maureen L.,Boykin, David W.,Abood, Norman
scheme or table, p. 3374 - 3377 (2010/02/28)
A series of bis-benzimidazole diamidine compounds containing different central linkers has been synthesized and evaluated for in vitro antibacterial activities, including drug-resistant bacterial strains. Seven compounds have shown potent antibacterial activities. The anti-MRSA and anti-VRE activities of compound 1h were more potent than that of the lead compound 1a and vancomycin.