33722-46-2

Basic information

• Product Name: 1H-Imidazole,4,5-dihydro-2,4,5-triphenyl-, (4R,5R)-rel-
• Synonyms: 1H-Imidazole,4,5-dihydro-2,4,5-triphenyl-, trans-(?à)-; 2-Imidazoline, 2,4,5-triphenyl-, (?à)- (8CI);(4R,5R)-rel-4,5-Dihydro-2,4,5-triphenyl-1H-imidazole; 1H-Imidazole,4,5-dihydro-2,4,5-triphenyl-, trans-; DL-Isoamarine; Isoamarine
• CAS NO: 33722-46-2
• Molecular Formula: C21H18 N2
• Molecular Weight: 298.387
• Mol File: 33722-46-2.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole,4,5-dihydro-2,4,5-triphenyl-, (4R,5R)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole,4,5-dihydro-2,4,5-triphenyl-, (4R,5R)-rel-(33722-46-2)
• EPA Substance Registry System: 1H-Imidazole,4,5-dihydro-2,4,5-triphenyl-, (4R,5R)-rel-(33722-46-2)

Safety Data

• Hazardous Substances Data: 33722-46-2(Hazardous Substances Data)

Usage

General Description

1H-Imidazole, 4,5-dihydro-2,4,5-triphenyl, (4R,5R)-rel- is a chemical compound with the molecular formula C21H19N. It is a stereochemically defined form of imidazole, a heterocyclic aromatic organic compound. The (4R,5R)-rel- configuration refers to the stereochemistry of the compound, with the R and S designations denoting the spatial arrangement of substituent groups around the chiral center. 1H-Imidazole, 4,5-dihydro-2,4,5-triphenyl, (4R,5R)-rel- has potential applications in medicinal chemistry, material science, and organic synthesis due to its unique structural and electronic properties. It may be used as a building block in the synthesis of various organic compounds and pharmaceuticals.

Upstream product

• 100-52-7 benzaldehyde 
• 57-13-6 urea 
• 65-85-0 benzoic acid 
• 92-29-5 hydrobenzamide 
• 951-87-1 meso-1,2-diphenyl-1,2-diaminoethane 
• 54874-97-4 N-(erythro-α'-amino-bibenzyl-α-yl)-benzamide 
• 92-29-5 (E,E)-1,3,5-triphenyl-2,4-diazapenta-1,4-diene 
• 573-33-1 (4R,5S)-2,4,5-Triphenyl-4,5-dihydro-1H-imidazole 
• 16118-22-2 benzylidenamine 
• 951-87-1 rac-1,2-diphenylethylene-1,2-diamine 
• 80424-18-6 (4R,5R)-2,4,5-Triphenyl-imidazolidine 
• 573-33-1 DL-(4R,5S)-2,4,5-triphenyl-4,5-dihydro-1H-imidazole 
• 573-33-1 amarine 
• 703-55-9 1-naphthylmagnesiumbromide 

Downstream Products

• 91840-93-6 (1S,2S)-N,N'-diethyl-1,2-diphenyl-1,2-ethanediamine 
• 216861-21-1 (1S,2S)-N,N'-(1,2-diphenylethane-1,2-diyl)diacetamide 
• 33722-47-3 DL-(4R,5S)-1-benzyl-2,4,5-triphenyl-4,5-dihydro-1H-imidazole 
• 40102-64-5 racem.-1,2-diphenyl-ethane-1,2-diamine; dihydrochloride 
• 951-87-1 rac-1,2-diphenylethylene-1,2-diamine 
• 911306-54-2 (+)-(1S,2S)-N-[(R)-α-acetoxyphenylacetyl]-N'-benzoyl-1,2-diamino-1,2-diphenylethane 
• 29841-69-8 (S,S)-1,2-diphenyl-1,2-diaminoethane 
• 911306-52-0 (-)-(4S,5S)-1-[(R)-α-acetoxyphenylacetyl]-4,5-dihydro-2,4,5-triphenyl-1H-imidazole 
• 161970-92-9 (+)-(4R,5R)-2,4,5-triphenyl-trans-4,5-dihydroimidazole 
• 133815-20-0 (-)-(4S,5S)-4,5-dihydro-2,4,5-triphenyl-1H-imidazole 
• 3190-22-5 erythro-N-benzoyl-N'-phenylmethylidene-1,2-diamino-1,2-diphenylethane 
• 484-47-9 lophine 
• 102457-31-8 (+/-)-2,4r,5t-tricyclohexyl-4,5-dihydro-1H-imidazole 
• 1140-29-0 N-(2-aminoethyl)-N-phenylaniline 

Relevant articles and documents

Convenient one-step synthesis of cis-2,4,5-triarylimidazolines from aromatic aldehydes with urea

A simple and efficient method has been developed for the synthesis of cis-2,4,5-triarylimidazolines based on a one-step procedure of aldehydes and urea in the presence of cesium carbonate. Taylor & Francis Group, LLC.

Cycloaddition reactions of 1,3-diazabuta-1,3-dienes with alkynyl ketenes

The cycloaddition reactions of 'all-carbon' 1,3-diazabuta-1,3-dienes with a few conjugated and unconjugated alkynyl ketenes are described. The reactions provide some interesting azetidinones and dihydropyrimidinones bearing an alkynyl moiety. The regiochemistry of cycloadduct is related with the degree of conjugation of the alkynyl ketene. Moreover, two alternative approaches to 'all-carbon' 1,3-diazabuta-1,3-dienes are reported.

One-pot synthesis of imidazolines from aldehydes: detailed study about solvents and substrates

Imidazolines were prepared in one-pot operation from aldehydes and diamines through oxidation of aminal intermediates by NBS. This method could be applied to various aromatic and aliphatic aldehydes and N-nonsubstituted and N-monosubstituted 1,2-diamines. Furthermore, it was found that CH2Cl2 could be altered to TBME, a more environmentally friendly solvent, in the reaction using N-nonsubstituted 1,2-diamines. The reaction conditions were very mild and chemoselective.