337520-16-8

Basic information

• Product Name: t-Butyl 4-(2-bromo-4-nitrophenoxy)piperidine-1-carboxylate
• Synonyms: t-Butyl 4-(2-bromo-4-nitrophenoxy)piperidine-1-carboxylate;tert-Butyl 4-(2-broMo-4-nitrophenoxy)piperidine-1-carboxylate
• CAS NO: 337520-16-8
• Molecular Formula: C₁₆H₂₁BrN₂O₅
• Molecular Weight: 401.27
• Mol File: 337520-16-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: t-Butyl 4-(2-bromo-4-nitrophenoxy)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: t-Butyl 4-(2-bromo-4-nitrophenoxy)piperidine-1-carboxylate(337520-16-8)
• EPA Substance Registry System: t-Butyl 4-(2-bromo-4-nitrophenoxy)piperidine-1-carboxylate(337520-16-8)

Safety Data

• Hazardous Substances Data: 337520-16-8(Hazardous Substances Data)

Usage

General Description

The chemical t-Butyl 4-(2-bromo-4-nitrophenoxy)piperidine-1-carboxylate, also known as Boc-4-bromo-2-nitrophenoxy-piperidine, is a complex organic compound with the molecular formula C16H22BrN2O5. It belongs to the class of piperidine carboxylic acids and is commonly used in the synthesis of pharmaceuticals and agrochemicals. t-Butyl 4-(2-bromo-4-nitrophenoxy)piperidine-1-carboxylate is characterized by the presence of a t-Butyl group and a 4-(2-bromo-4-nitrophenoxy) substituent linked to the piperidine-1-carboxylate backbone. It is a white to off-white crystalline powder with a molecular weight of 388.26 g/mol. Its precise properties and applications make it an important intermediate in the production of various organic compounds.

Upstream product

• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 

Downstream Products

• 1299487-34-5 2-(4-((4-(4-amino-2-bromophenoxy)piperidin-1-yl)methyl)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol 
• 1299487-33-4 2-(4-((4-(2-bromo-4-nitrophenoxy)piperidin-1-yl)methyl)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol 
• 1299487-32-3 4-(2-bromo-4-nitrophenoxy)piperidine 
• 1299487-31-2 1-(3-bromo-4-(1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl)piperidin-4-yloxy)phenyl)-3-(tetrahydro-2H-pyran-4-yl)urea 
• 337520-17-9 3-bromo-4-(1-t-butoxycarbonylpiperidin-4-yloxy)aniline 

Relevant articles and documents

BENZAMIDINE DERIVATIVES

Benzamidine derivatives of formula (I) or pharmaceutically acceptable salts thereof exhibit excellent inhibitory activity against factor Xa and are useful for treating or preventing blood coagulation disorders: wherein R 1represents a hydrogen atom, a halogen atom, an alkyl group or a hydroxyl group; R 2represents a hydrogen atom, a halogen atom or an alkyl group, R 3represents a hydrogen atom, an optionally substituted alkyl group, an aralkyl group, an optionally substituted alkanoyl group or an optionally substituted alkylsulfonyl group, R 4and R 5 are the same as or different from each other and each represent a hydrogen atom, a halogen atom, an optionally substituted alkyl group, an alkoxy group, a carboxyl group, an alkoxycarbonyl group or an optionally substituted carbamoyl group, and R 6represents a substituted pyrrolidine group or substituted piperidine group.