33837-83-1Relevant articles and documents
ALPHAvBETA1 INTEGRIN ANTAGONISTS
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Paragraph 0171; 0251-0252, (2020/01/31)
The present disclosure provides pharmaceutical agents, including those of the formula: (I) wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical agents. Methods of using the pharmaceutical agents are also provided. The compounds may be used for the inhibition or antagonism of integrins ανβ1 and/or α5β1. In some embodiments, the compounds provided herein exhibit reduced inhibitory or antagonistic activity of integrins ανβ3, ανβ5, ανβ6, ανβ8, and/or αIIbβ3.
Encapsulation and release mechanisms in coordination polymer nanoparticles
Amorin-Ferre, Laura,Busque, Felix,Bourdelande, Jose Luis,Ruiz-Molina, Daniel,Hernando, Jordi,Novio, Fernando
, p. 17508 - 17516 (2014/01/06)
The interplay of guest encapsulation and release mechanisms in nanoscale metal-organic vehicles and its effect on the drug-delivery kinetics of these materials were investigated through a new multidisciplinary approach. Two rationally-designed molecular g
An efficient method for the synthesis of lignans
Wang, Qian,Yang, Yong,Li, Ying,Yu, Wei,Hou, Zi Jie
, p. 6107 - 6112 (2007/10/03)
An efficient approach for the synthesis of several types of lignans (dibenzylbutanediols, dibenzylbutanes, substituted tetrahydrofurans, aryldihydronaphthalenes, arylnaphthalenes, and aryltetralins) was developed. The regioselective oxidative coupling of ethyl ferulate was used as the key step.