33890-03-8

Basic information

• Product Name: 4-Aminoisophthalic acid
• Synonyms: 4-Aminoisophthalic acid;4-Amino-1,3-benzenedicarboxylic acid;4-Aminobenzene-1,3-dicarboxylic acid;5-Carboxyanthranilic acid
• CAS NO: 33890-03-8
• Molecular Formula: C₈H₇NO₄
• Molecular Weight: 181.15
• Mol File: 33890-03-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 336-337℃
• Boiling Point: 458.1 °C at 760 mmHg
• Flash Point: 230.8 °C
• Appearance: /
• Density: 1.551
• Vapor Pressure: 3.47E-09mmHg at 25°C
• Refractive Index: 1.684
• PKA: 4.49±0.10(Predicted)
• CAS DataBase Reference: 4-Aminoisophthalic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Aminoisophthalic acid(33890-03-8)
• EPA Substance Registry System: 4-Aminoisophthalic acid(33890-03-8)

Safety Data

• Hazardous Substances Data: 33890-03-8(Hazardous Substances Data)

Usage

Chemical Properties

Off-white powder

InChI:InChI=1/C8H7NO4/c9-6-2-1-4(7(10)11)3-5(6)8(12)13/h1-3H,9H2,(H,10,11)(H,12,13)

Upstream product

• 478788-48-6 monoamide of trimellitic acid 
• 7726-95-6 bromine 
• 95-63-6 1,2,4-Trimethylbenzene 
• 54699-35-3 1,2-dimethyl 1,2,4-benzenetricarboxylate 
• 1670-81-1 1H-Indole-5-carboxylic acid 
• 125376-17-2 C₁₈H₁₀N₂O₆ 
• 3113-71-1 3-methyl-4-nitrobenzoic acid 
• 89-87-2 2,4-dimethylnitrobenzene 
• 41684-07-5 4-amino-3-(methoxycarbonyl)benzoic acid 
• 2050-43-3 N-(2,4-dimethylphenyl)acetamide 
• 13912-71-5 benzene-1,2,4-tricarboxylic acid-1-methyl ester 
• 2459-10-1 benzene-1,2,4-tricarboxylic acid trimethyl ester 
• 528-44-9 1,2,4-benzene tricarboxylic acid 
• 63746-12-3 dimethyl 4-aminoisophthalate 

Downstream Products

• 64018-94-6 diethyl 4-aminoisophthalate 
• 872266-70-1 4-amino-isophthalic acid-1-ethyl ester 
• 80776-94-9 11-Oxo-6,8,9,11-tetrahydro-7H-pyrido[2,1-b]quinazoline-2-carboxylic acid 
• 63746-25-8 4-amino-benzene-1,3-dicarboxylic acid,1-methyl ester 
• 63746-12-3 dimethyl 4-aminoisophthalate 
• 1374778-21-8 4-(3-chlorobenzo[b]thiophene)-2-carboxamido-3-(4-chlorophenylcarbamoyl)benzoic acid 
• 1374779-58-4 C₁₄H₁₁ClN₂O₃ 
• 4435-99-8 4-(carboxymethylamino)isophthalic acid 
• 33986-75-3 4-oxo-3,4-dihydroquinazoline-6-carboxylic acid 
• 280774-09-6 4-(4-tert-Butylbenzoylamino)isophthalic Acid 
• 33986-75-3 6-carboxyquinazolin-4-one 
• 1026477-86-0 4-amino-3-[(4-methoxy)-benzylcarbamoyl]-phenyl-1-carboxylic acid 4-methoxy-benzylamide 
• 79043-89-3 4-acetylamino-isophthalic acid diethyl ester 
• 871886-64-5 4-(acetyl-methyl-amino)-isophthalic acid 

Relevant articles and documents

Anthranilic acid and derivatives thereof as well as synthesis method and application thereof

In the reaction solvent, o-methyl (hetero) aryl nitro compound is taken as a reaction raw material and is used for water. The anthranilic acid and its derivatives are synthesized by the action of a catalyst, a base and an additive. The synthetic method has the advantages of cheap and easily available raw materials, simple reaction operation, high yield and excellent functional group tolerance, and provides a simple and efficient method for synthesizing o-aminobenzoic acid which is widely used in the aspects of dyes, medicines, pesticides, spices and the like. The invention further discloses the anthranilic acid and derivatives and application thereof, and has a wide application prospect.

NEUROTRYPSIN INHIBITORS

The invention relates to acylamino-phthalic acid amides and related compounds of formula (I) wherein A is -CONR3R4,-NR5COR6, -NHR7, -OR8, -mR9, -CH2NRI0R11, -(CH2)2-R12, -CH=CH-R12, -C=C-R12, optionally substituted phenyl, optionally substituted thiophenyl, or optionally substituted 1,2,3-triazol-4-yl, W is hydrogen, hydroxy or carboxymethoxy, Y is carboxy, methoxycarbonyl or 2H-tetrazol-5-yl, and the various substituents R have the meanings indicated in the description. These compounds are useful for the treatment and/or prophylaxis of skeletal muscle atrophy, schizophrenia and Alzheimer?s disease, and as cognitive enhancers.

Bromamine-B/PdCl2 is an efficient system for the synthesis of anthranilic acids from indoles and indigos

A convenient method has been developed for the conversion of indoles and indigos into anthranilic acids in good to excellent yields using a bromamine-B/PdCl2 system. The general process utilizes our efficient method for the oxidation of indoles and indigos in alkaline (pH 12) acetonitrile/water (1:1) at 60°C. Copyright Taylor & Francis Group, LLC.