339266-17-0

Basic information

• Product Name: C₂₁H₃₈BrNO₅Si
• CAS NO: 339266-17-0
• Molecular Weight: 492.526
• Mol File: 339266-17-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₃₈BrNO₅Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₃₈BrNO₅Si(339266-17-0)
• EPA Substance Registry System: C₂₁H₃₈BrNO₅Si(339266-17-0)

Safety Data

• Hazardous Substances Data: 339266-17-0(Hazardous Substances Data)

Upstream product

• 339266-16-9 tert-Butoxycarbonylamino-acetic acid (1S,6S)-2-bromo-6-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-cyclohex-2-enyl ester 
• 67451-62-1 cis-(1S,2S)-1,2-dihydroxy-3-bromocyclohexa-3,5-diene 
• 214415-99-3 (1S,6S)-2-Bromo-6-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-cyclohex-2-enol 
• 174817-06-2 cis-(1S,2S)-1,2-dihydroxy-3-bromocyclohex-3-ene 

Relevant articles and documents

Total synthesis of dihydrocodeine and hydrocodone via a double claisen rearrangement and C-10/C-11 closure strategy

Dihydrocodeine and hydrocodone were synthesized from bromobenzene in 16 and 17 transformations, respectively. The key steps involved the toluene dioxygenase-mediated dihydroxylation of bromobenzene by whole-cell fermentation with E. coli JM109(pDTG601A), Kazmaier-Claisen rearrangement of glycinate ester, Claisen rearrangement to set the C-13 quaternary center, and C-10-C-11 closure. Experimental procedures are provided for the key steps. Georg Thieme Verlag Stuttgart . New York.