3399-21-1

Basic information

• Product Name: CIS-1,4-DIMETHYL CYCLOHEXANEDICARBOXYLATE
• Synonyms: CIS-1,4-DIMETHYL CYCLOHEXANEDICARBOXYLATE;(1s,4s)-diMethyl cyclohexane-1,4-dicarboxylate;cis-Dimethyl cyclohexane-1,4-dicarboxylate
• CAS NO: 3399-21-1
• Molecular Formula: C₁₀H₁₆O₄
• Molecular Weight: 200.23
• Mol File: 3399-21-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: 14°C
• Boiling Point: 297.96°C (rough estimate)
• Appearance: /
• Density: 1.1112
• Refractive Index: 1.4568 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: CIS-1,4-DIMETHYL CYCLOHEXANEDICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: CIS-1,4-DIMETHYL CYCLOHEXANEDICARBOXYLATE(3399-21-1)
• EPA Substance Registry System: CIS-1,4-DIMETHYL CYCLOHEXANEDICARBOXYLATE(3399-21-1)

Safety Data

• Hazardous Substances Data: 3399-21-1(Hazardous Substances Data)

Usage

General Description

CIS-1,4-DIMETHYL CYCLOHEXANEDICARBOXYLATE is a chemical compound that is classified as a dicarboxylate ester. It is derived from cyclohexane and contains two carboxylate functional groups. CIS-1,4-DIMETHYL CYCLOHEXANEDICARBOXYLATE is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It is also utilized in the production of plasticizers and other industrial chemicals. CIS-1,4-DIMETHYL CYCLOHEXANEDICARBOXYLATE is a colorless liquid with a molecular formula of C10H16O4 and a molecular weight of 200.23 g/mol. It is important to handle this compound with care and ensure proper storage to prevent any potential hazards.

Upstream product

• 67-56-1 methanol 
• 619-81-8 cis-cyclohexane-1,4-dicarboxylic acid 
• 94-60-0 dimethyl 1,4-cyclohexane dicarboxylate 
• 186581-53-3 diazomethane 
• 120-61-6 1,4-benzenedicarboxylic acid dimethyl ester 
• 1078-58-6 diphenylzinc 
• 7647-01-0 hydrogenchloride 
• 64-19-7 acetic acid 
• 79368-45-9 7-Oxobicyclo<2.2.1>heptan-1-carbonylchlorid 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 3236-48-4 trans-1,4-Cyclohexanedimethanol 
• 3236-47-3 (1s,4s)-cyclohexane-1,4-diyldimethanol 
• 1011-85-4 (1S,4S)-4-(methoxycarbonyl)cyclohexane-1-carboxylic acid 
• 852899-22-0 cis-1.4-bis-(α-methoxy-benzhydryl)-cyclohexane 
• 15898-77-8 (Z)-1,4-bis(bromomethyl)cyclohexane 
• 100252-61-7 cis-4-allylcarbamoyl-cyclohexanecarboxylic acid methyl ester 
• 100055-56-9 cis-4-allylcarbamoyl-cyclohexanecarboxylic acid 
• 96581-95-2 1,4-dibenzhydrylidene-cyclohexane 
• 888709-79-3 cis-1,4-Bis-(2-hydroxy-isopropyl)-cyclohexan 
• 188038-19-9 cis-1,4-di(diphenylhydroxymethyl)cyclohexane 
• 58940-71-9 trans-Bis-1,4-(1'-methyl-1'-hydroxy-ethyl)-cyclohexan 
• 71707-72-7 3,5-dinitro-benzoic acid-(4-methylene-cyclohexylmethyl ester) 
• 116076-50-7 (1,4-cis-cyclohexanediyl)bis(methylene)dimethanesultonate 
• 37180-67-9 cis-1,4-bis-(acetylsulfanyl-methyl)-cyclohexane 

Relevant articles and documents

Highly-efficient Ru/Al-SBA-15 catalysts with strong Lewis acid sites for the water-assisted hydrogenation of: P -phthalic acid

Ruthenium nanoparticles supported onto aluminum-doped mesoporous silica catalysts (Ru/Al-SBA-15) are fabricated using hydrothermal and impregnation methods for catalysis application. The Ru/Al-SBA-15-3 catalyst at a Si/Al molar ratio of 3 exhibited excellent catalytic performance for the hydrogenation of p-phthalic acid with high conversion efficiency (100.0%) and cis-isomer selectivity (84.0%) in water. Moreover, this system displays exceptional stability and recyclability through preserving the conversion efficiency, as well as a cis-isomer selectivity of 90.2 and 83.3%, respectively, after reusing it fourteen times. Such an exceptional system can also be ideal for the hydrogenation of aromatic dicarboxylic acids and their ester derivatives in water. Strong Lewis acid sites due to doped Al species play significant roles in the hydrogenation reaction. Moreover, isotope labeling studies indicated that water molecules effectively participated in the hydrogenation reaction. Hydrogen and water contributed half of the hydrogen atoms for this hydrogenation reaction. In the end, a plausible mechanistic pathway for the hydrogenation of p-phthalic acid using the Ru/Al-SBA-15-3 catalyst in water is proposed.

Ni-Catalyzed Site-Selective Dicarboxylation of 1,3-Dienes with CO2

A site-selective catalytic incorporation of multiple CO2 molecules into 1,3-dienes en route to adipic acids is described. This protocol is characterized by its mild conditions, excellent chemo- and regioselectivity and ease of execution under CO2 (1 atm), including the use of bulk butadiene and/or isoprene feedstocks.

Cross-coupling reaction of oxo-π-allylnickel complex generated from 1,3-diene under an atmosphere of carbon dioxide

-