3399-56-2Relevant articles and documents
Iodine-Catalyzed Regioselective Oxidative Cyclization of Aldehyde Hydrazones with Electron-Deficient Olefins for the Synthesis of Mefenpyr-Diethyl
Deng, Yun-Xia,Lin, Hao-Peng,Wang, Wen-Kang,Zhao, Sheng-Yin,Zheng, Jian,Zhu, Jia-Nan
, (2019/08/26)
A regioselective synthesis of polysubstituted dihydropyrazoles and pyrazoles through an iodine-catalyzed oxidative cyclization strategy of aldehyde hydrazones with electron-deficient olefins is described. The protocol adopts very mild reaction conditions and provides desirable yields. The reaction is supposed to proceed via a cascade C-H functionalization, C-N bond formation, and oxidation sequential processes. The overall simplicity and regioselectivity of the catalytic system make this approach a valuable and step-economical tool to construct a C-C bond for the synthesis of Mefenpyr-Diethyl.
A ONE STEP SYNTHESIS OF 4-CYANOPYRAZOLES
Hassaneen, Hamdi M.,Ead, Hamed A.,Elwan, Nehal M.,Shawali, Ahmed S.
, p. 2857 - 2862 (2007/10/02)
Reaction of nitrilimines 2 with fumaronitrile 6 yielded 4-cyanopyrazoles 8 in good yields.The structures of 8 were substantiated by comparison with their regioisomers 5-cyanopyrazoles 5, prepared by addition of 2 to acrylonitrile followed by oxidation of
