340188-50-3Relevant articles and documents
Turn Conformation of β-Amino Acid-Based Short Peptides Promoted by an Amidothiourea Moiety at C-Terminus
Zhang, Yanhan,Yan, Xiaosheng,Cao, Jinlian,Weng, Peimin,Miao, Daiyu,Li, Zhao,Jiang, Yun-Bao
, p. 9844 - 9849 (2020/09/03)
A C-terminal amidothiourea motif is shown to promote a β-turn-like folded conformation in a series of β-amino acid-based short peptides in both the solid state and solution phase by an intramolecular 11-membered ring hydrogen bond.
USE OF CONDENSED BENZO[B]THIAZINE DERIVATIVES AS CYTOPROTECTANTS
-
Page/Page column 67, (2014/12/12)
The present invention relates to arylthiazine compounds, metabolites, N-oxides, amides, esters,pharmaceutically acceptable salts, hydrates and solvates thereof and their use as cytoprotectants in the treatment or prophylaxis of diseases or states, either acute or chronic, involving aberrant cellular lipid peroxidation in the central nervous system or in the periphery of the body. The present invention also relates to a method for their preparation and to pharmaceutical composition comprising as an active ingredient one or more of the aforementioned compounds.
Highly efficient iridium-catalyzed asymmetric hydrogenation of unprotected β-enamine esters
Hou, Guohua,Zhang, Xumu,Li, Wei,Ma, Miaofeng,Zhang, Xiaowei
supporting information; experimental part, p. 12844 - 12846 (2010/11/05)
A highly efficient and enantioselective hydrogenation of unprotected β-enamine esters catalyzed by Ir-(S,S)-f-Binaphane complex has been developed. This methodology provides straightforward access to free β-amino acids in high yields with excellent enantioselectivities up to 97% ee and high reactivities (TON > 5000).
