34058-62-3Relevant articles and documents
Nickel-catalyzed aromatic C-H alkylation with secondary or tertiary alkyl-bromine bonds for the construction of indolones
Liu, Chao,Liu, Dong,Zhang, Wei,Zhou, Liangliang,Lei, Aiwen
, p. 6166 - 6169 (2013)
A nickel-catalyzed aromatic C-H alkylation with tertiary or secondary alkyl-Br bonds for the construction of indolones was demonstrated. Various functional groups were well tolerated. Moreover, the challenging secondary alkyl bromides were well introduced in this transformation. Radical trapping and photocatalysis conditions exhibited that it is most likely to be a radical process for this aromatic C-H alkylation.
Enantioselective Synthesis of C?N Axially Chiral N-Aryloxindoles by Asymmetric Rhodium-Catalyzed Dual C?H Activation
Li, Honghe,Yan, Xiaoqiang,Zhang, Jitan,Guo, Weicong,Jiang, Jijun,Wang, Jun
, p. 6732 - 6736 (2019/04/17)
The first enantioselective Satoh–Miura-type reaction is reported. A variety of C?N axially chiral N-aryloxindoles have been enantioselectively synthesized by an asymmetric rhodium-catalyzed dual C?H activation reaction of N-aryloxindoles and alkynes. High yields and enantioselectivities were obtained (up to 99 % yield and up to 99 % ee). To date, it is also the first example of the asymmetric synthesis of C?N axially chiral compounds by such a C?H activation strategy.
A tethering directing group strategy for ruthenium-catalyzed intramolecular alkene hydroarylation
Kilaru, Praveen,Acharya, Sunil P.,Zhao, Pinjing
, p. 924 - 927 (2018/02/07)
We report a new catalyst design for N-heterocycle synthesis that utilizes an alkene-tethered amide moiety as a directing group for aromatic C-H activation. This tethering directing group strategy is demonstrated in a ruthenium-catalyzed intramolecular alk
