34199-21-8

Basic information

• Product Name: Quercetin 5-glucoside
• Synonyms: 3,3',4',7-Tetrahydroxy-5-(β-D-glucopyranosyloxy)flavone;Quercetin 5-glucoside;Saxifragin
• CAS NO: 34199-21-8
• Molecular Formula: C₂₁H₂₀O₁₂
• Molecular Weight: 464.38
• Mol File: 34199-21-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 264 °C
• Boiling Point: 885.3±65.0 °C(Predicted)
• Appearance: /
• Density: 1.809±0.06 g/cm3(Predicted)
• PKA: 6.23±0.40(Predicted)
• CAS DataBase Reference: Quercetin 5-glucoside(CAS DataBase Reference)
• NIST Chemistry Reference: Quercetin 5-glucoside(34199-21-8)
• EPA Substance Registry System: Quercetin 5-glucoside(34199-21-8)

Safety Data

• Hazardous Substances Data: 34199-21-8(Hazardous Substances Data)

Upstream product

• 117-39-5 quercetol 
• 1313191-76-2 3,7-bisbenzyloxy-2-(3,4-bisbenzyloxyphenyl)-5-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranosyloxy-4H-chromen-4-one 
• 1486-63-1 3,7-bis(benzyloxy)-2-[3,4-bis(benzyloxy)phenyl]-5-hydroxy-4H-1-benzopyran-4-one 

Relevant articles and documents

Regiospecific synthesis of quercetin O-β-d-glucosylated and O-β-d-glucuronidated isomers

Quercetin, the polyphenolic compound, which has the highest daily intake, is well known for its protective effects against aging diseases and has received a lot of attention for this reason. Both quercetin 3-O-β-d-glucuronide and quercetin 3′-O-β-d-glucuronide are human metabolites, which, together with their regioisomers, are required for biological as well as physical chemistry studies. We present here a novel synthetic route based on the sequential and selective protections of the hydroxyl functions of quercetin allowing selective glycosylation, followed by TEMPO-mediated oxidation to the glucuronide. This methodology enabled us to synthesize the five O-β-d-glucosides and four O-β-d-glucuronides of quercetin, including the major human metabolite, quercetin 3-O-β-d-glucuronide.