342908-16-1 Usage
General Description
2-Amino-6-quinolinecarboxylic acid ethylester is a chemical compound with the molecular formula C12H12N2O2. It is an ethyl ester derivative of 2-amino-6-quinolinecarboxylic acid, which is a quinolone antibiotic that has been used in the treatment of various bacterial infections. 2-AMINO-6-QUINOLINECARBOXYLIC ACID ETHYLESTER is mainly used in chemical research as a building block for the synthesis of other organic compounds. It has also been studied for its potential biological activities and pharmacological properties. 2-Amino-6-quinolinecarboxylic acid ethylester may have applications in the development of new drugs and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 342908-16-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,2,9,0 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 342908-16:
(8*3)+(7*4)+(6*2)+(5*9)+(4*0)+(3*8)+(2*1)+(1*6)=141
141 % 10 = 1
So 342908-16-1 is a valid CAS Registry Number.
342908-16-1Relevant articles and documents
Optimization of a coagulation factor VIIa inhibitor found in factor Xa inhibitor library
Sagi, Kazuyuki,Fujita, Koichi,Sugiki, Masayuki,Takahashi, Mitsuo,Takehana, Shunji,Tashiro, Kazumi,Kayahara, Takashi,Yamanashi, Masahiro,Fukuda, Yumiko,Oono, Seiji,Okajima, Akiko,Iwata, Seinosuke,Shoji, Masataka,Sakurai, Kuniya
, p. 1487 - 1496 (2007/10/03)
An inhibitor of the complex of factor VIIa and tissue factor (fVIIa/TF), 2-substituted-4-amidinophenylpyruvic acid 1a, was structurally modified with the aim of increasing its potency and selectivity. The lead compound 1a was originally found in our factor Xa (fXa) inhibitor library on the basis of structural similarity of the primary binding sites of fVIIa and fXa. The design was based on computational docking studies using the extracted active site of fVIIa. Compound 1j was found to inhibit factor VIIa/TF at nanomolar concentration with improved selectivity versus fXa and thrombin and it preferentially prolonged the clotting time in the TF-dependent extrinsic pathway.
