3430-95-3

Basic information

• Product Name: N-phenyldodecanamide
• Synonyms: dodecanamide, N-phenyl-; N-Phenyldodecanamide
• CAS NO: 3430-95-3
• Molecular Formula: C₁₈H₂₉NO
• Molecular Weight: 275.429
• Mol File: 3430-95-3.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 429.9°C at 760 mmHg
• Flash Point: 264.8°C
• Density: 0.957g/cm³
• Vapor Pressure: 1.35E-07mmHg at 25°C
• Refractive Index: 1.515
• CAS DataBase Reference: N-phenyldodecanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyldodecanamide(3430-95-3)
• EPA Substance Registry System: N-phenyldodecanamide(3430-95-3)

Safety Data

• Hazardous Substances Data: 3430-95-3(Hazardous Substances Data)

Usage

General Description

N-phenyldodecanamide, also known as N-phenyl lauric amide, is a chemical compound that belongs to the class of amides. It is derived from lauric acid, a saturated fatty acid, and contains a phenyl group attached to the nitrogen atom. N-phenyldodecanamide is commonly used as an intermediate in the production of surfactants, lubricants, and corrosion inhibitors. It is known for its ability to reduce friction and improve the lubricating properties of various materials. Additionally, it can act as a dispersing agent in various formulations and has been used in the formulation of personal care products and pharmaceuticals.

Upstream product

• 63833-77-2 1-lauroyl-pyridinium; chloride 
• 62-53-3 aniline 
• 31334-43-7 lauric acid hydrazide; hydrochloride 
• 1120-16-7 lauric acid amide 
• 143-07-7 lauric acid 
• 14565-47-0 N-succinimidyl laurate 
• 43009-32-1 Lauroyl azide 
• 60-29-7 diethyl ether 
• 112-16-3 n-dodecanoyl chloride 

Downstream Products

• 124-22-1 n-Dodecylamine 
• 3007-74-7 N-dodecylaniline 
• 122-39-4 diphenylamine 
• 62-53-3 aniline 
• 917610-39-0 1-(2-aminophenyl)dodecan-1-one 
• 858487-82-8 C₂₄H₃₄N₂ 
• 1309477-17-5 C₃₃H₃₈N₂O₂ 
• 1401412-97-2 N-(hexadecan-5-yl)benzenamine 
• 1311478-35-9 C₄₄H₇₄N₄O₂ 
• 917610-46-9 [5-tert-butoxycarbonylamino-5-(2-dodecanoyl-phenylcarbamoyl)-pentyl]-carbamic acid benzyl ester 
• 917610-45-8 [(2-dodecanoyl-phenylcarbamoyl)-methyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Acylamino-Directed Specific Sequential Difunctionalizations of Anilides via Metal-Free Relay Reactions for p-Oxygen and o-Nitrogen Incorporation

Novel acylamino-directed relay disubstitutions realize the sequential difunctionalizations of anilides (1) under mild and metal-free conditions for the first time. This [bis(trifluoroacetoxy)iodo]benzene (PIFA) and BF3·Et2O promoted straightforward reaction produces a series of p-acetoxyl- or p-alkoxyl-o-nitro-N-arylamides (2), which are key scaffolds of various drugs, functional materials, and bioactive molecules. The flexibility with respect to the functional groups in these products affords this novel protocol excellent versatility for synthetic applications.

Graphene oxide (GO) catalyzed transamidation of aliphatic amides: An efficient metal-free procedure

Transamidation involves direct interconversion of an amide with amine, and represents an alternative to the common method of amide formation from the reaction of carboxylic acid with an amine. While the carboxamides have huge potential in biological systems and polymer industries, their formation from carboxylic acids requires activation by a suitable catalyst. A metal-free transamidation of aliphatic amide with aromatic amine catalyzed by graphene oxide (GO) has been developed and established as a general, synthetically useful and selective procedure. Graphene oxide bearing several carboxylic acids on the edges and having large surface area acts as an efficient and recyclable catalyst for transamidation.

Amidation of Carboxylic Acids with Amines by Nb2O5 as a Reusable Lewis Acid Catalyst

Among 28 types of heterogeneous and homogenous catalysts tested, Nb2O5 shows the highest yield for direct amidation of n-dodecanoic acid with a less reactive amine (aniline). The catalytic amidation by Nb2O5 is applicable to a wide range of carboxylic acids and amines with various functional groups, and the catalyst is reusable. A comparison of the results of the catalytic study and an infrared study of the acetic acid adsorbed on the catalyst suggests that activation of the carbonyl group of the carboxylic acid by Lewis acid sites on Nb2O5 is responsible for the high activity of the Nb2O5 catalyst. Kinetic studies show that Lewis acid sites on Nb2O5 are more water-tolerant than conventional Lewis acidic oxides (Al2O3, TiO2). In comparison with the state-of-the-art homogeneous Lewis acid catalyst for amidation (ZrCl4), Nb2O5 undergoes fewer negative effects from basic additives in the solution, which indicates that Nb2O5 is a more base-tolerant Lewis acid catalyst than the homogeneous Lewis acid catalyst.