345264-16-6

Basic information

• Product Name: Pyrrolo[3,2,1-jk][1,4]benzodiazepine-7(1H)-acetic acid, 2-[(1,1-dimethylethoxy)carbonyl]-3,4-dihydro-Alpha-oxo-, methyl ester
• Synonyms: Pyrrolo[3,2,1-jk][1,4]benzodiazepine-7(1H)-acetic acid, 2-[(1,1-dimethylethoxy)carbonyl]-3,4-dihydro-Alpha-oxo-, methyl ester;Pyrrolo[3,2,1-jk][1,4]benzodiazepine-7(1H)-acetic acid, 2-[(1,1-dimethylethoxy)carbonyl]-3,4-dihydro-α-oxo-, methyl ester
• CAS NO: 345264-16-6
• Molecular Formula: C19H22N2O5
• Molecular Weight: 358.38838
• Mol File: 345264-16-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyrrolo[3,2,1-jk][1,4]benzodiazepine-7(1H)-acetic acid, 2-[(1,1-dimethylethoxy)carbonyl]-3,4-dihydro-Alpha-oxo-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolo[3,2,1-jk][1,4]benzodiazepine-7(1H)-acetic acid, 2-[(1,1-dimethylethoxy)carbonyl]-3,4-dihydro-Alpha-oxo-, methyl ester(345264-16-6)
• EPA Substance Registry System: Pyrrolo[3,2,1-jk][1,4]benzodiazepine-7(1H)-acetic acid, 2-[(1,1-dimethylethoxy)carbonyl]-3,4-dihydro-Alpha-oxo-, methyl ester(345264-16-6)

Safety Data

• Hazardous Substances Data: 345264-16-6(Hazardous Substances Data)

Upstream product

• 79-37-8 oxalyl dichloride 
• 124-41-4 sodium methylate 
• 345264-15-5 S-6-(tert-butoxycarbonyl)-5,6-dihydro-6H-[1,4]diazepino[6,7,1-hi]indole 
• 748811-03-2 2-[(tert-butoxycarbonyl)(1H-indol-7-ylmethyl)amino]ethyl methanesulfonate 
• 748811-02-1 tert-butyl (2-hydroxyethyl)(1Hindol-7-ylmethyl)carbamate 
• 408356-56-9 2-[(1H-indol-7-ylmethyl)-amino]-ethanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1074-88-0 1H-indole-7-carbaldehyde 

Downstream Products

• 603281-60-3 LY2090314 

Relevant articles and documents

Preparation of novel aza-1,7-annulated indoles and their conversion to potent indolocarbazole kinase inhibitors

The synthesis of novel aza-1,7-annulated indoles was achieved and these were converted to indolocarbazoles that proved to be potent kinase inhibitors. These compounds were also evaluated in a human colon carcinoma cell line and proved to be good antiproliferative agents.

AGENTS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES

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