345264-26-8Relevant articles and documents
Preparation of novel aza-1,7-annulated indoles and their conversion to potent indolocarbazole kinase inhibitors
Al-awar, Rima S.,Ray, James E.,Hecker, Kyle A.,Joseph, Sajan,Huang, Jianping,Shih, Chuan,Brooks, Harold B.,Spencer, Charles D.,Watkins, Scott A.,Schultz, Richard M.,Considine, Eileen L.,Faul, Margaret M.,Sullivan, Kevin A.,Kolis, Stanley P.,Carr, Michael A.,Zhang, Faming
, p. 3925 - 3928 (2007/10/03)
The synthesis of novel aza-1,7-annulated indoles was achieved and these were converted to indolocarbazoles that proved to be potent kinase inhibitors. These compounds were also evaluated in a human colon carcinoma cell line and proved to be good antiproliferative agents.
