3453-39-2 Usage
Description
(2E)-3-(6-Methoxy-2-naphthyl)acrylic acid is a yellow crystalline powder that is a derivative of acrylic acid with a substituted naphthyl group. It is commonly used in organic synthesis and chemical research due to its structural characteristics and potential biological activities.
Uses
Used in Pharmaceutical and Medicinal Chemistry:
(2E)-3-(6-Methoxy-2-naphthyl)acrylic acid is used as a building block in the synthesis of other compounds for its potential applications in pharmaceutical and medicinal chemistry. Its aromatic structure and potential biological activities make it a promising candidate for the development of new drugs and therapeutic agents.
Used in Organic Synthesis:
(2E)-3-(6-Methoxy-2-naphthyl)acrylic acid is used as an important intermediate in the production of pharmaceuticals and agrochemicals. Its unique structure allows for the creation of various compounds with specific properties, making it a valuable component in the field of organic synthesis.
Used in the Development of New Materials:
(2E)-3-(6-Methoxy-2-naphthyl)acrylic acid's aromatic structure makes it a useful component in the development of new materials and compounds with specific properties. Its versatility in chemical reactions and potential for creating novel materials make it an important asset in material science and related industries.
Check Digit Verification of cas no
The CAS Registry Mumber 3453-39-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,5 and 3 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3453-39:
(6*3)+(5*4)+(4*5)+(3*3)+(2*3)+(1*9)=82
82 % 10 = 2
So 3453-39-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H12O3/c1-17-13-6-5-11-8-10(3-7-14(15)16)2-4-12(11)9-13/h2-9H,1H3,(H,15,16)/b7-3+
3453-39-2Relevant articles and documents
Evaluation of synthetic naphthalene derivatives as novel chemical chaperones that mimic 4-phenylbutyric acid
Mimori, Seisuke,Koshikawa, Yukari,Mashima, Yu,Mitsunaga, Katsuyoshi,Kawada, Koichi,Kaneko, Masayuki,Okuma, Yasunobu,Nomura, Yasuyuki,Murakami, Yasuoki,Kanzaki, Tetsuto,Hamana, Hiroshi
, p. 811 - 814 (2015/02/19)
The chemical chaperone 4-phenylbutyric acid (4-PBA) has potential as an agent for the treatment of neurodegenerative diseases. However, the requirement of high concentrations warrants chemical optimization for clinical use. In this study, novel naphthalene derivatives with a greater chemical chaperone activity than 4-PBA were synthesized with analogy to the benzene ring. All novel compounds showed chemical chaperone activity, and 2 and 5 possessed high activity. In subsequent experiments, the protective effects of the compounds were examined in Parkinson's disease model cells, and low toxicity of 9 and 11 was related to amphiphilic substitution with naphthalene.
