34648-99-2

Basic information

• Product Name: 4-CHLORO-5-NITRO-2-TOLUIDINE
• Synonyms: 4-CHLORO-5-NITRO-2-TOLUIDINE;4-Chloro-5-nitro-o-toluidine (NH2=1);4-Chloro-2-methyl-5-nitroaniline;4-Chloro-2-methyl-5-nitro-phenylamine
• CAS NO: 34648-99-2
• Molecular Formula: C₇H₇ClN₂O₂
• Molecular Weight: 186.6
• Mol File: 34648-99-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 369.2°Cat760mmHg
• Flash Point: 177.1°C
• Appearance: /
• Density: 1.415g/cm³
• Vapor Pressure: 1.2E-05mmHg at 25°C
• Refractive Index: 1.627
• CAS DataBase Reference: 4-CHLORO-5-NITRO-2-TOLUIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-5-NITRO-2-TOLUIDINE(34648-99-2)
• EPA Substance Registry System: 4-CHLORO-5-NITRO-2-TOLUIDINE(34648-99-2)

Safety Data

• Hazardous Substances Data: 34648-99-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H7ClN2O2/c1-4-2-5(8)7(10(11)12)3-6(4)9/h2-3H,9H2,1H3

Upstream product

• 51676-74-5 1-chloro-5-methyl-2,4-dinitrobenzene 
• 95-69-2 4-chloro-2-methylbenzeneamine 
• 7664-93-9 sulfuric acid 
• 7697-37-2 nitric acid 
• 2028-72-0 m-toluenediazonium chloride 
• 108-41-8 1-chloro-3-methylbenzene 

Downstream Products

• 381229-50-1 2-methoxyphenyl-4-amino-2-nitro-5-methylphenyl sulfide 
• 95-80-7 4-methylbenzene-1,3-diamine 
• 43216-72-4 2,4-diamino-5-chlorotoluene 
• 615-65-6 2-chloro-4-methyl-benzenamine 
• 18931-78-7 N-(2-chloro-4-methylphenyl)acetamide 
• 381229-51-2 2-methoxyphenyl 4-iodo-2-nitro-5-methylphenyl sulfide 
• 34649-00-8 N-(2-methyl-4-chloro-5-nitrophenyl)acetamide 
• 38939-88-7 2-chloro-4-methyl-1-nitrobenzene 
• 178448-14-1 4-chloro-2-methyl-5-nitrobenzonitrile 

Relevant articles and documents

Mono-nitration of aromatic compounds via their nitric acid salts

Aromatic compounds bearing a basic nitrogen atom can be converted to the corresponding nitric acid salts. Mono-nitration of the compounds can be carried out by adding a dichloromethane solution of the salts to sulfuric acid, or by adding acetyl chloride (or trifluoroacetic anhydride) to a dichloromethane solution of the salts. This protocol provides, among other benefits, the most convenient and reliable way for the prevention of over-/under-nitration and is especially suitable for scale-up.

Substituted 2-alkylamino-4-amino-1-alkylbenzene compounds and oxidation hair dye compositions based on said compounds

The new coupler compounds of the invention are 4-amino-2 -(2'-hydroxyethyl)-amino-5-methoxytoluene and/or 4-amino-2-(2'-hydroxyethyl)amino-5-chlorotoluene. The invention also includes an oxidation hair dye composition including an effective amount, advant