3473-12-9

Basic information

• Product Name: 2-Phenethylthiosemicarbazide
• Synonyms: 2-Phenethylthiosemicarbazide;2-Phenethyl-3-thiosemicarbazide;Brn 3092698;Hydrazinecarbothioamide, 1-(2-phenylethyl)- (9ci);Semicarbazide, 2-phenethyl-3-thio-
• CAS NO: 3473-12-9
• Molecular Formula: C₉H₁₃N₃S
• Molecular Weight: 195.31
• Mol File: 3473-12-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 355.8°Cat760mmHg
• Flash Point: 169°C
• Appearance: /
• Density: 1.1220 (rough estimate)
• Vapor Pressure: 3.06E-05mmHg at 25°C
• Refractive Index: 1.5300 (estimate)
• CAS DataBase Reference: 2-Phenethylthiosemicarbazide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenethylthiosemicarbazide(3473-12-9)
• EPA Substance Registry System: 2-Phenethylthiosemicarbazide(3473-12-9)

Safety Data

• Hazardous Substances Data: 3473-12-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H13N3S/c10-9(13)12(11)7-6-8-4-2-1-3-5-8/h1-5H,6-7,11H2,(H2,10,13)

Upstream product

• 506-68-3 bromocyane 
• 51-71-8 Phenelzine 
• 1147550-11-5 ammonium thiocyanate 
• 156-51-4 2-phenethylhydrazine sulfate 
• 333-20-0 potassium thioacyanate 
• 5470-36-0 [2-(phenyl)ethyl]hydrazine hydrochloride 

Downstream Products

• 1562528-36-2 6-hydroxy-2-phenethyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one 
• 1562528-42-0 methyl 2-(2-carbamothioyl-2-phenethylhydrazinyl)-2-oxoacetate 

Relevant articles and documents

6-Hydroxy-1,2,4-triazine-3,5(2H,4H)-dione Derivatives as Novel d -Amino Acid Oxidase Inhibitors

A series of 2-substituted 6-hydroxy-1,2,4-triazine-3,5(2H,4H)-dione derivatives were synthesized as inhibitors of d-amino acid oxidase (DAAO). Many compounds in this series were found to be potent DAAO inhibitors, with IC50 values in the double-digit nanomolar range. The 6-hydroxy-1,2,4-triazine-3,5(2H,4H)-dione pharmacophore appears metabolically resistant to O-glucuronidation unlike other structurally related DAAO inhibitors. Among them, 6-hydroxy-2-(naphthalen-1-ylmethyl)-1,2,4-triazine-3,5(2H,4H)-dione 11h was found to be selective over a number of targets and orally available in mice. Furthermore, oral coadministration of d-serine with 11h enhanced the plasma levels of d-serine in mice compared to the oral administration of d-serine alone, demonstrating its ability to serve as a pharmacoenhancer of d-serine.