3480-56-6

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-(1-phenylethenyl)-
• CAS NO: 3480-56-6
• Molecular Formula: C16H11NO2
• Molecular Weight: 249.269
• Mol File: 3480-56-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-(1-phenylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-(1-phenylethenyl)-(3480-56-6)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-(1-phenylethenyl)-(3480-56-6)

Safety Data

• Hazardous Substances Data: 3480-56-6(Hazardous Substances Data)

Usage

Derivative of

Cinnamic acid

Class of organic compounds

Cinnamic acids and derivatives

Uses

Pharmaceutical and chemical applications, reagent in the synthesis of organic compounds, production of dyes, perfumes, and other industrial products

Potential biological activities

Antioxidant and anti-inflammatory properties, potential medicinal uses.

Upstream product

• 24540-00-9 2-methyl-2-phthalimidophenylacetyl chloride 
• 74-85-1 ethene 
• 100-42-5 styrene 
• 136918-14-4 phthalimide 
• 3695-00-9 di(4-tosyl)amine 
• 1074-82-4 potassium phtalimide 

Downstream Products

• 935278-12-9 C₁₇H₁₃NO₃ 
• 83256-46-6 3-(1,3-dioxoisoindolin-2-yl)-3-phenylpropanoic acid 

Relevant articles and documents

Palladium-catalyzed oxidative amination of alkenes: Improved catalyst reoxidation enables the use of alkene as the limiting reagent

Palladium-catalyzed methods for intermolecular aerobic oxidative amination of alkenes have been identified that are compatible with the use of alkene as the limiting reagent. These procedures, which enhance the utility of this reaction with alkenes that a

Aerobic oxidative amination of unactivated alkenes catalyzed by palladium

The first examples of palladium-catalyzed oxidative amination of unactivated alkyl olefins have been identified. To be successful, these reactions must be conducted under cocatalyst-free conditions that involve direct dioxygen-coupled turnover of the palladium catalyst. The oxidative amination products of norbornene and other cyclic alkenes implicate a cis-aminopalladation mechanism. Copyright

Dioxygen-Coupled Oxidative Amination of Styrene

Dioxygen-coupled oxidative amination of olefins is an attractive, but challenging, catalytic transformation. The present work describes the first general method for intermolecular oxidative amination of aryl olefins with molecular oxygen as the stoichiometric oxidant. This palladium-catalyzed reactivity is compatible with several different nitrogen nucleophiles, including oxazolidinone, phthalimide, pyrrolidinone, and p-toluenesulfonamide. The presence of a catalytic quantity of a Bronsted base in the reaction increases the catalytic activity and switches the reaction regioselectivity. Copyright