34859-65-9

Basic information

• Product Name: ETHYL 5-AMINO-3-METHYLISOTHIAZOLE-4-CARBOXYLATE
• Synonyms: ART-CHEM-BB B014678;ETHYL 5-AMINO-3-METHYLISOTHIAZOLE-4-CARBOXYLATE;Ethyl 5-amino-3-methylisothiazole-4-carboxylate 97%;ethyl 5-amino-3-methylisothiazole-4-carboxylate(SALTDATA: FREE);4-Isothiazolecarboxylic acid, 5-aMino-3-Methyl-, ethyl ester;Ethyl5-amino-3-methylisothiazole-4-carboxylate97%;Ethyl 5-amino-3-methyl-1,2-thiazole-4-carboxylate
• CAS NO: 34859-65-9
• Molecular Formula: C₇H₁₀N₂O₂S
• Molecular Weight: 186.23
• Mol File: 34859-65-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 111 °C
• Boiling Point: 221.2 °C at 760 mmHg
• Flash Point: 87.6 °C
• Appearance: /
• Density: 1.283 g/cm³
• Vapor Pressure: 0.108mmHg at 25°C
• Refractive Index: 1.578
• PKA: 6.40±0.50(Predicted)
• CAS DataBase Reference: ETHYL 5-AMINO-3-METHYLISOTHIAZOLE-4-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 5-AMINO-3-METHYLISOTHIAZOLE-4-CARBOXYLATE(34859-65-9)
• EPA Substance Registry System: ETHYL 5-AMINO-3-METHYLISOTHIAZOLE-4-CARBOXYLATE(34859-65-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 34859-65-9(Hazardous Substances Data)

Usage

General Description

ETHYL 5-AMINO-3-METHYLISOTHIAZOLE-4-CARBOXYLATE is a chemical compound with the molecular formula C8H11N3O2S. It is a derivative of isothiazole, containing an ethyl ester group, an amino group, and a carboxylate group. ETHYL 5-AMINO-3-METHYLISOTHIAZOLE-4-CARBOXYLATE has potential applications in the field of pharmaceuticals and agrochemicals due to its ability to act as a building block for the synthesis of various biologically active molecules. It may also have utility as an intermediate in organic synthesis for the production of specialized materials and compounds. ETHYL 5-AMINO-3-METHYLISOTHIAZOLE-4-CARBOXYLATE is known for its characteristic odor and should be handled and stored according to recommended safety procedures.

InChI:InChI=1/C7H10N2O2S/c1-3-11-7(10)5-4(2)9-12-6(5)8/h3,8H2,1-2H3

Upstream product

• 64-17-5 ethanol 
• 41808-35-9 5-amino-4-cyano-3-methylisothiazole 
• 626-34-6 ethyl aminocrotonate 
• 63089-25-8 2-(1-amino-ethylidene)-N-phenoxycarbonyl-3-thio-malonamic acid ethyl ester 
• 49779-15-9 3-methyl-5-phenoxycarbonylamino-isothiazole-4-carboxylic acid ethyl ester 

Downstream Products

• 90030-94-7 3-methyl-7H-isothiazolo[5,4-d]pyrimidine-4,6-dione 
• 90091-24-0 3-methyl-5-ureido-isothiazole-4-carboxylic acid ethyl ester 
• 60870-75-9 6a,7,8,9,10,11-hexahydro-6H-isothiazolo[5'',4'':4',5']pyrimido[2',1':2,3]imidazo[1,5-a]azepin-4-one 
• 22131-51-7 5-amino-3-methyl-1,2-thiazole-4-carboxylic acid 
• 25039-59-2 3-methyl-5-nitrosoamino-isothiazole-4-carboxylic acid ethyl ester 
• 24979-20-2 3,3'-dimethyl-5,5'-triazene-1,3-diyl-bis-isothiazole-4-carboxylic acid diethyl ester 
• 70375-66-5 5-imino-2,3-dimethyl-2,5-dihydro-isothiazole-4-carboxylic acid ethyl ester 
• 90007-57-1 5-formylamino-3-methyl-isothiazole-4-carboxylic acid ethyl ester 
• 1262031-45-7 C₁₉H₁₈N₂O₃S 
• 1063629-98-0 ethyl 5-(3-bromopropanamido)-3-methylisothiazole-4-carboxylate 
• 925091-73-2 ethyl 5-(2-chloroacetamido)-3-methylisothiazole-4-carboxylate 
• 40297-64-1 3-methyl-5-(3-methyl-ureido)-isothiazole-4-carboxylic acid ethyl ester 
• 95709-11-8 3-methyl-5-phenyl-6-thioxo-6,7-dihydro-5H-isothiazolo[5,4-d]pyrimidin-4-one 
• 32277-87-5 C₂₄H₁₈Cl₂N₆O₄S₂ 

Relevant articles and documents

ISOTHIAZOLO[5,4-D]PYRIMIDINE COMPOUND AS IRAK4 INHIBITOR

Disclosed in the present invention are an IRAK4 inhibitor, and an application thereof in preparation of a drug for treating IRAK4-related diseases. Specifically disclosed are a compound represented by formula (III) and a pharmaceutically acceptable salt thereof.