348642-87-5

Basic information

• Product Name: 3-[4-benzyloxy-2-(1,2-dimethyl-propenyl)-phenyl]-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester
• Synonyms: 3-[4-benzyloxy-2-(1,2-dimethyl-propenyl)-phenyl]-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester
• CAS NO: 348642-87-5
• Molecular Weight: 579.852
• Mol File: 348642-87-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-[4-benzyloxy-2-(1,2-dimethyl-propenyl)-phenyl]-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-benzyloxy-2-(1,2-dimethyl-propenyl)-phenyl]-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester(348642-87-5)
• EPA Substance Registry System: 3-[4-benzyloxy-2-(1,2-dimethyl-propenyl)-phenyl]-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester(348642-87-5)

Safety Data

• Hazardous Substances Data: 348642-87-5(Hazardous Substances Data)

Upstream product

• 81658-27-7 (S)-tert-butyl 2-(((tert-butyldimethylsilyl)oxy)methyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 348642-85-3 4-bromo-3-(1-hydroxy-2,2-dimethyl-propyl)-phenol 
• 100-83-4 meta-hydroxybenzaldehyde 
• 2973-80-0 2-bromo-5-hydroxybenzaldehyde 
• 348642-86-4 4-Benzyloxy-1-bromo-2-(1,2-dimethyl-propenyl)-benzene 

Downstream Products

• 348642-88-6 6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxymethyl)-8-isopropyl-8-methyl-1-oxo-3,3a,8,8a-tetrahydro-1H-2-aza-cyclopenta[a]indene-2-carboxylic acid tert-butyl ester 
• 348642-89-7 6-benzyloxy-3-(tert-butyl-dimethyl-silanyloxymethyl)-8-isopropyl-8-methyl-1-oxo-3,3a,8,8a-tetrahydro-1H-2-aza-cyclopenta[a]indene-2-carboxylic acid tert-butyl ester 

Relevant articles and documents

Rigid pyrrolidone modulators of pkc

Compounds of the general formula (I): wherein substituents at R1, R2, R3 and R4 have any of the values defined in the specification, and their pharmaceutically acceptable salts, are PKC modulators and are useful for treating diseases, such as, for example, cancers including prostate cancer, inflammatory, autoimmune and neurological disorders including Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising compounds of formula (I), processes for preparing compounds of formula (I), and intermediates useful for preparing compounds of formula (I).