35048-10-3

Basic information

• Product Name: 8-Quinolinol, 7-fluoro-
• Synonyms: 8-Quinolinol, 7-fluoro-;7-Fluoro-8-quinolinol;8-Quinolinol, 7-fluoro- 7-Fluoro-8-quinolinol
• CAS NO: 35048-10-3
• Molecular Formula: C₉H₆FNO
• Molecular Weight: 163.15
• Mol File: 35048-10-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 296℃
• Flash Point: 133℃
• Appearance: /
• Density: 1.366
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.66
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 2.04±0.50(Predicted)
• CAS DataBase Reference: 8-Quinolinol, 7-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Quinolinol, 7-fluoro-(35048-10-3)
• EPA Substance Registry System: 8-Quinolinol, 7-fluoro-(35048-10-3)

Safety Data

• Hazardous Substances Data: 35048-10-3(Hazardous Substances Data)

Usage

General Description

8-Quinolinol, 7-fluoro- is a chemical compound that belongs to the class of quinoline derivatives. It is also known by the chemical name 7-fluoro-8-hydroxyquinoline and has the molecular formula C9H6FNO. 8-Quinolinol, 7-fluoro- is a pale yellow solid that is used in various industrial and research applications, including as a building block in the synthesis of pharmaceuticals and agrochemicals. 8-Quinolinol, 7-fluoro- has a wide range of biological activities, including antimicrobial, antifungal, and antiviral properties. It is also used as a chelating agent and is known for its ability to form complexes with metal ions, making it useful in analytical chemistry and metal extraction processes.

InChI:InChI=1/C9H6FNO/c10-7-4-3-6-2-1-5-11-8(6)9(7)12/h1-5,12H

Upstream product

• 1526-17-6 2-fluoro-6-nitrophenol 
• 56-81-5 glycerol 
• 3054-95-3 acrylaldehyde diethyl acetal 
• 53981-25-2 2-amino-6-fluoro phenol 

Relevant articles and documents

Nitrohydroxyquinoline derivative and preparation method and application thereof

The invention discloses a nitrohydroxyquinoline derivative and a preparation method and application thereof. Specifically, the invention discloses a compound shown as a general formula (I), a preparation method of the compound, a pharmaceutical composition containing the compound, and an application of the compound in treatment on infectious diseases or cancers. The compound disclosed by the invention has different anti-tumor activities and can be developed into a medicine for treating tumors. The definition of each group in the general formula (I) is the same as that in the specification.

COMT INHIBITING METHODS AND COMPOSITIONS

The present inventions include a method of inhibiting COMT enzyme in a subject as well as compounds of formula I, or a pharmaceutically acceptable salt thereof, that are useful in the treatment of various disorders mediated by COMT, including Parkinson's disease and/or schizophrenia.

NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF

8-Hydroxy-quinoline derivatives and 8-ethers, 8-esters, 8-carbonates, 8-acyloxymethyl, 8- phosphates, (phosphoryloxy)methyl, and 8-carbamates derivatives thereof are described that exhibit iron chelation, neuroprotective, neurorestorative, apoptotic and/or selective MAO-AB inhibitory activities.