350609-88-0Relevant articles and documents
Synthetic analogues of naturally occurring spider toxins: Synthesis of 2-(Hydroxyphenyl)propanamides of spermidine and spermine
Popaj, Kasim,Guggisberg, Armin,Hesse, Manfred
, p. 797 - 816 (2007/10/03)
In a study on structure-activity relationships of spider toxins, six model compounds, namely the spermidine derivatives 6, 8, and 16 as well as the spermine derivatives 24, 27, and 32 were synthesized. The synthesis proceeds through stepwise construction of the polyamine backbone, including protection and deprotection of the amino functions. The differentiation of the derivatives by analytical and spectroscopic methods is discussed.