35081-79-9

Basic information

• Product Name: 4-(4-PYRIDINETHIOACETYL)MORPHOLINE
• Synonyms: LABOTEST-BB LT00455858;4-(4-PYRIDINETHIOACETYL)MORPHOLINE;4-PYRIDYLTHIOACETYL MORPHOLIDE
• CAS NO: 35081-79-9
• Molecular Formula: C₁₁H₁₄N₂OS
• Molecular Weight: 222.31
• Mol File: 35081-79-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 104.5-105.5 °C
• Boiling Point: 379.2°Cat760mmHg
• Flash Point: 183.1°C
• Appearance: /
• Density: 1.224g/cm³
• Vapor Pressure: 5.95E-06mmHg at 25°C
• Refractive Index: 1.606
• PKA: 5.36±0.10(Predicted)
• CAS DataBase Reference: 4-(4-PYRIDINETHIOACETYL)MORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-PYRIDINETHIOACETYL)MORPHOLINE(35081-79-9)
• EPA Substance Registry System: 4-(4-PYRIDINETHIOACETYL)MORPHOLINE(35081-79-9)

Safety Data

• Hazardous Substances Data: 35081-79-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14N2OS/c15-11(13-5-7-14-8-6-13)9-10-1-3-12-4-2-10/h1-4H,5-9H2

Upstream product

• 110-91-8 morpholine 
• 1122-54-9 methyl (4-pyridyl) ketone 
• 536-75-4 4-Ethylpyridine 
• 100-43-6 4-vinylpyridine 

Downstream Products

• 54401-85-3 pyridin-4-yl-acetic acid ethyl ester 
• 101793-06-0 4-(3-phenyl-2-[4]pyridyl-acryloyl)-morpholine 
• 37969-01-0 N-(3,4-dimethoxy-phenethyl)-2-pyridin-4-yl-acetamide 
• 108477-30-1 4-(3-phenyl-2-[4]pyridyl-propionyl)-morpholine 
• 109156-63-0 [4]piperidyl-acetic acid-(3,4-dimethoxy-phenethylamide) 
• 102658-91-3 [1-(3,4-dimethoxy-phenethyl)-[4]piperidyl]-acetic acid ethyl ester 
• 754124-67-9 1-[1-(3,4-dimethoxy-phenethyl)-piperidin-4-ylmethyl]-6,7-dimethoxy-3,4-dihydro-isoquinoline 
• 17289-64-4 1-[1-(3,4-dimethoxy-phenethyl)-piperidin-4-ylmethyl]-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline 
• 37969-10-1 N-(3,4-dimethoxy-phenethyl)-2-[1-(3,4-dimethoxy-phenethyl)-piperidin-4-yl]-acetamide 
• 117868-22-1 1-(3,4-dimethoxy-phenethyl)-4-[(3,4-dimethoxy-phenethylcarbamoyl)-methyl]-pyridinium; iodide 
• 1393898-17-3 5-(morpholin-4-yl)-3-phenyl-4-(pyridin-4-yl)thiophen-2(3H)-one 
• 73415-84-6 2-(piperidin-4-yl)acetic acid hydrochloride 
• 6622-91-9 2-(pyridine-4-yl)acetic acid hydrochloride 
• 28487-18-5 N-[2-(4-pyridyl)ethyl]morpholine 

Relevant articles and documents

Design, synthesis and evaluation of novel 2-thiophen-5-yl-3H-quinazolin-4-one analogues as inhibitors of transcription factors NF-k{cyrillic}B and AP-1 mediated transcriptional activation: Their possible utilization as anti-inflammatory and anti-cancer ag

In an attempt to discover novel inhibitors of NF-κB and AP-1 mediated transcriptional activation utilizing the concept of chemical lead based medicinal chemistry and bioisosterism a series of 2-(2,3-disubstituted-thiophen-5-yl)-3H-quinazolin-4-one analogs

Microwave-assisted rapid hydrolysis and preparation of thioamides by Willgerodt-Kindler reaction

Aldehydes and aryl alkyl ketones were efficiently transformed to thioamides with the same number of carbon atoms via Willgerodt-Kindler reaction under microwave irradiation in solvent-free conditions. The thioamides obtained were hydrolyzed to corresponding carboxylic acids with microwave dielectric heating in one minute. Both reactions are very fast and the yields are excellent.