352000-07-8

Basic information

• Product Name: BAICALEIN, MONOHYDRATE
• Synonyms: 5,6,7-TRIHYDROXYFLAVONE, MONOHYDRATE;BAICALEIN, MONOHYDRATE
• CAS NO: 352000-07-8
• Molecular Formula: C15H12O6
• Molecular Weight: 288.25
• Product Categories: Aromatics, Heterocycles, Inhibitors
• Mol File: 352000-07-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Acetone, Ethanol, Methanol
• CAS DataBase Reference: BAICALEIN, MONOHYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: BAICALEIN, MONOHYDRATE(352000-07-8)
• EPA Substance Registry System: BAICALEIN, MONOHYDRATE(352000-07-8)

Safety Data

• Hazardous Substances Data: 352000-07-8(Hazardous Substances Data)

Usage

Description

Baicalein, Monohydrate is a flavonoid compound derived from various plant sources, including Nepalese and Sino-Japanese crude drugs. It possesses potent anti-inflammatory, antioxidant, and anti-cancer properties, making it a valuable compound for pharmaceutical and therapeutic applications.

Uses

Used in Pharmaceutical Applications:
Baicalein, Monohydrate is used as an inhibitor for various biological processes, including 12-lipoxygenase, leukotriene biosynthesis, and the release of lysosomal enzymes. It plays a crucial role in modulating cellular Ca2+ uptake and mobilization, which contributes to its anti-inflammatory and anti-arthritic effects.
Used in Anti-Inflammatory Applications:
Baicalein, Monohydrate is used as an anti-inflammatory agent to alleviate the symptoms of adjuvant-induced arthritis and other inflammatory conditions. Its ability to inhibit leukotriene biosynthesis and the release of lysosomal enzymes helps reduce inflammation and associated pain.
Used in Antioxidant Applications:
Baicalein, Monohydrate is used as an antioxidant, protecting cells from oxidative stress and damage caused by free radicals. Its antioxidant properties contribute to its overall therapeutic potential in various diseases and conditions.
Used in Anticancer Applications:
Baicalein, Monohydrate is used as an anticancer agent, targeting various cancer cell types and exhibiting potential synergistic effects when combined with conventional chemotherapeutic drugs. Its ability to modulate oncological signaling pathways and enhance chemo-sensitivity makes it a promising candidate for cancer treatment.
Used in Drug Delivery Systems:
To improve the bioavailability and therapeutic outcomes of Baicalein, Monohydrate, various drug delivery systems have been developed. These systems, including organic and metallic nanoparticles, serve as carriers for the compound, enhancing its delivery and efficacy against target cells and tissues.