353-81-1

Basic information

• Product Name: 2,2-difluorobutane
• Synonyms: 2,2-difluorobutane
• CAS NO: 353-81-1
• Molecular Formula: C₄H₈F₂
• Molecular Weight: 94.1031264
• Mol File: 353-81-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: -117.5°C
• Boiling Point: 30.85°C
• Appearance: /
• Density: 0.9282 (rough estimate)
• Vapor Pressure: 542mmHg at 25°C
• Refractive Index: 1.3192
• CAS DataBase Reference: 2,2-difluorobutane(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-difluorobutane(353-81-1)
• EPA Substance Registry System: 2,2-difluorobutane(353-81-1)

Safety Data

• Hazardous Substances Data: 353-81-1(Hazardous Substances Data)

Usage

General Description

2,2-difluorobutane is a synthetic organic compound with the chemical formula C4H8F2. It belongs to the class of fluoroalkanes, which are organic compounds containing fluorine atoms. 2,2-difluorobutane is a colorless, odorless gas at room temperature and is highly flammable. It is commonly used as a refrigerant and as a propellant in aerosol sprays. The compound is also used in the production of pharmaceuticals and agrochemicals. However, it is important to handle 2,2-difluorobutane with caution as it is a potential environmental hazard with a high global warming potential.

InChI:InChI=1/C4H8F2/c1-3-4(2,5)6/h3H2,1-2H3

Upstream product

• 420-96-2 2-chloro-2-fluoro-butane 
• 4279-22-5 2,2-dichlorobutane 
• 624-64-6 trans-2-Butene 
• 513-38-2 Isobutyl iodide 
• 7783-56-4 antimony(III) fluoride 
• 2211-70-3 2-chloro-but-1-ene 
• 7664-39-3 hydrogen fluoride 
• 503-17-3 dimethylacetylene 
• 107-00-6 but-1-yne 
• 66675-39-6 (E)-2-fluoro-2-butene 
• 78-93-3 butanone 
• 373-90-0 3,3-difluoro-1-butene 
• 4461-41-0 2-chloro-but-2-ene 

Downstream Products

• 7664-39-3 hydrogen fluoride 

Relevant articles and documents

Hydrofluorination of Unsaturated Compounds with Solid Potassium Hydrogen Fluoride in the Presence of Silicon Tetrafluoride at Room Temperature

Hydrofluorination of unsaturated compounds proceeds by reaction with solid potassium hydrogen fluoride and silicon tetrafluoride to afford the corresponding fluorides in high yields.

Method of Synthesis of Arylsulfur Trifluorides and Use as in situ Deoxofluorination Reagent

The invention is a method of synthesizing Arylsulfur Trifluorides, such as Fluolead, by reacting BR2 and KF (or suitable alkali metal fluoride) in acetonitrile (or other suitable solvent). The invention also comprises using the Fluolead (or its

vic-difluorination of fluoroalkenes with xenon difiuoride: The effect of fluorine substituents on the reaction of alkenes with xenon difluoride

vic-Difluorination proceeds by the reaction of fluoroalkenes with xenon difluoride to afford the corresponding fluorinated compounds. From the reaction with polyfluoroalkenes, the products are obtained in high to excellent yields. In this reaction, the fluorine atom substituent of alkene stabilizes the cation intermediate and suppresses side-reactions such as rearrangement.