35342-88-2

Basic information

• Product Name: N,O-BIS(TRIMETHYLSILYL)CARBAMATE
• Synonyms: trimethylsilyl trimethylsilylcarbamate;TRIMETHYLSILYL N-(TRIMETHYLSILYL)- &;TRIMETHYLSILYL N-TRIMETHYLSILYL CARBAMATE 99+%;N,0-Bis(Trimethylsilyl)carbamate;Carbamic acid, (trimethylsilyl)-, trimethylsilyl ester;BSC, Trimethylsilyl N-(trimethylsilyl)carbamate;(Trimethylsilyl)carbamic acid trimethylsilyl ester;Anti-SLC12A2 antibody produced in goat
• CAS NO: 35342-88-2
• Molecular Formula: C₇H₁₉NO₂Si₂
• Molecular Weight: 205.4
• EINECS: 252-520-4
• Mol File: 35342-88-2.mol
• Article Data: 8

Chemical Properties

• Melting Point: 71-80 °C(lit.)
• Boiling Point: 77 °C
• Flash Point: °C
• Appearance: /
• Density: 0.901g/cm³
• Refractive Index: 1.416
• Storage Temp.: -20°C
• BRN: 2043399
• CAS DataBase Reference: N,O-BIS(TRIMETHYLSILYL)CARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: N,O-BIS(TRIMETHYLSILYL)CARBAMATE(35342-88-2)
• EPA Substance Registry System: N,O-BIS(TRIMETHYLSILYL)CARBAMATE(35342-88-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 35342-88-2(Hazardous Substances Data)

Usage

General Description

N,O-BIS(TRIMETHYLSILYL)CARBAMATE is a chemical compound primarily used as a reagent in organic synthesis. It is a derivative of carbamic acid and is often employed in the protection of amines and other nitrogen-containing functional groups in organic molecules. N,O-BIS(TRIMETHYLSILYL)CARBAMATE is highly stable and can be easily handled and stored. It is commonly utilized in the field of pharmaceuticals and agrochemicals for the synthesis of various compounds due to its versatility in protecting amine groups. N,O-BIS(TRIMETHYLSILYL)CARBAMATE is also known for its compatibility with a wide range of solvents and reaction conditions, making it a versatile reagent in organic chemistry.

InChI:InChI=1/C7H19NO2Si2/c1-11(2,3)8-7(9)10-12(4,5)6/h1-6H3,(H,8,9)

Upstream product

• 10416-59-8 N,O-bis-(trimethylsilyl)-acetamide 
• 1111-78-0 ammonium carbamate 
• 70726-27-1 trimethylsilyl ester of N-trimethylsilyl-N-trimethylsiloxycarbamic acid 
• 124-38-9 carbon dioxide 
• 107-11-9 1-amino-2-propene 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 288-32-4 1H-imidazole 
• 4244-84-2 ethyl β-alaninate hydrochloride 
• 3196-73-4 methyl 3-aminopropanoate hydrochloride 
• 945419-77-2 C₁₁H₁₄O₂NCl*HCl 
• 502842-12-8 3-Amino-3-p-tolyl-propionic acid ethyl ester; hydrochloride 
• 945419-73-8 C₁₄H₂₁O₃N*HCl 
• 167887-35-6 3-amino-3-(4-methoxyphenyl)propionic acid ethyl ester hydrochloride 

Downstream Products

• 76241-32-2 C₁₀H₁₃NO₃SSi 
• 69563-03-7 N-(2,6-dimethylphenyl)-N-trimethylsilylamine 
• 76241-31-1 2,6-dimethyl-N-(trimethylsiloxycarbonyl)aniline 
• 3768-55-6 N-trimethylsilylaniline 
• 30882-95-2 N-(trimethylsilyl)carbamatobenzene 
• 30593-25-0 N-(trimethylsilyl)carbamatocyclohexane 

Relevant articles and documents

Unusual course of diazolees silylation and N-siloxycarbonylation

The N-siloxycarbonylation and transamination reactions were studied by an example of diazoles. We found that because of insufficient nucleophilicity of the nitrogen atoms in the first case only the sililylation process occurs, in the second case the low-boiling amine is replaced by the higher boiling one and the process is completed by the formation of O-silyluretans. Pleiades Publishing, Ltd., 2011.

Carbacephalosporin compound, their preparation and use

Carbacephalosporin compounds of formula (I), STR1 salts thereof, processes for their synthesis and uses thereof, wherein: R1 is hydrogen, methoxy or formamido; R2 is an acyl group; CO2 R3 is a carboxy group or a carboxylate anion, or R3 is a carboxy protecting group or a pharmaceutically acceptable salt-forming group or in vivo hydrolysable ester group; R4, R5, R6 and R7 represent hydrogen or a substituent; R4 and R7 may be replaced by a chemical bond between the two carbon atoms shown; R5 and R6 may be linked together into a cyclic system. The compounds (I) have antibacterial properties.

SILICON DERIVATIVES OF HYDROXYCARBAMIC ACIDS. SYNTHESIS, PROPERTIES, AND X-RAY STRUCTURAL ANALYSIS OF SILYL CARBAMATES

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