35400-15-8

Basic information

• Product Name: 4-(Acetyloxy)benzeneacetic acid methyl ester
• Synonyms: 4-(Acetyloxy)benzeneacetic acid methyl ester
• CAS NO: 35400-15-8
• Molecular Formula: C₁₁H₁₂O₄
• Molecular Weight: 0
• Mol File: 35400-15-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(Acetyloxy)benzeneacetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Acetyloxy)benzeneacetic acid methyl ester(35400-15-8)
• EPA Substance Registry System: 4-(Acetyloxy)benzeneacetic acid methyl ester(35400-15-8)

Safety Data

• Hazardous Substances Data: 35400-15-8(Hazardous Substances Data)

Upstream product

• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 75-36-5 acetyl chloride 
• 7757-82-6 sodium sulfate 
• 108-24-7 acetic anhydride 

Downstream Products

• 959694-68-9 Methyl 2-(4-acetoxyphenyl)-2-bromoacetate 
• 203071-82-3 [3-Acetyl-4-(3-bromo-propoxy)-phenyl]-acetic acid methyl ester 
• 185802-77-1 3-acetyl-4-(3-bromopropoxy)phenylacetic acid 
• 203071-83-4 [4-(3-Bromo-propoxy)-3-ethyl-phenyl]-acetic acid methyl ester 
• 185802-75-9 4-(3-bromopropoxy)-3-ethylphenylacetic acid 
• 145042-91-7 (3-acetyl-4-hydroxyphenyl)acetic acid methyl ester 

Relevant articles and documents

Preparation method for synthesis of phenolic ester through thiocarboxylic acid mediated visible light catalyzed phenol acylation reaction

The invention discloses a preparation method for synthesis of phenolic ester through a thiocarboxylic acid mediated visible light catalyzed phenol acylation reaction. Thiocarboxylic acid compounds andphenol compounds are subjected to a site specific reaction under certain conditions to produce phenolic ester compounds, wherein the certain conditions are as follows: under the conditions of normaltemperature, normal pressure and visible light, K2CO3 is used as an alkaline catalyst, terpyridyl ruthenium dichloride hexahydrate is used as a photosensitizer and acetonitrile is used as a reaction solvent. Synthesis of phenolic ester under catalysis of visible light is realized, thiocarboxylic acid is used as an acylation reagent, and the site specific phenol esterification reaction is realizedefficiently under mild conditions of normal temperature, normal pressure and visible light. The method has mild reaction conditions, large substrate functional group tolerance, high applicability andhigh yield, and an efficient, reliable and economical preparation method is provided for synthesis of phenolic ester.

KHMDS enhanced SmI2-mediated reformatsky type α-cyanation

A novel combination of SmI2, KHMDS, and TsCN can be utilized to introduce a cyano group into structurally diverse and highly sensitive 2-alkyl-chroman-4-ones. Subsequent oxidation allows the formed 2-alkyl-3-cyanochromones to be isolated in yields ranging from 49 to 77%. In addition, α-bromoketones and esters were found to undergo equally effective α-cyanation.