355-30-6

Basic information

• Product Name: NONAFLUOROPENTALDEHYDE HYDRATE
• Synonyms: NONAFLUOROPENTALDEHYDE HYDRATE;2,2,3,3,4,4,5,5,5-Nonafluoro-1,1-pentanediol;1H-Perfluoropentane-1,1-diol;2,2,3,3,4,4,5,5,5-Nonafluoropentane-1,1-diol;1H-Nonafluoropentane-1,1-diol;2,2,3,3,4,4,5,5,5-Nonafluoropentane-1,1-diol, Nonafluoropentaldehyde hydrate (diol)
• CAS NO: 355-30-6
• Molecular Formula: C5H3F9O2
• Molecular Weight: 266.06
• Mol File: 355-30-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 28.7°C at 760 mmHg
• Appearance: /
• Density: 1.573g/cm³
• Vapor Pressure: 661mmHg at 25°C
• Refractive Index: 1.269
• CAS DataBase Reference: NONAFLUOROPENTALDEHYDE HYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: NONAFLUOROPENTALDEHYDE HYDRATE(355-30-6)
• EPA Substance Registry System: NONAFLUOROPENTALDEHYDE HYDRATE(355-30-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 355-30-6(Hazardous Substances Data)

Usage

General Description

NONAFLUOROPENTALDEHYDE HYDRATE is a chemical compound that is primarily used in the manufacturing of pharmaceuticals and other specialty chemicals. It is a hydrate form of nonafluoropentaldehyde, which is highly reactive and versatile in organic synthesis. NONAFLUOROPENTALDEHYDE HYDRATE is a strong oxidizing agent and can be used in the production of fluorinated compounds, as well as in the synthesis of fluorinated building blocks for other chemicals. It is also used as a reactant in the preparation of other fluorinated compounds, and has potential applications in the field of materials science and nanotechnology. Overall, NONAFLUOROPENTALDEHYDE HYDRATE is a valuable and versatile chemical in the field of organic synthesis and specialty chemical manufacturing.

InChI:InChI=1/C5HF9O/c6-2(7,1-15)3(8,9)4(10,11)5(12,13)14/h1H

Upstream product

• 2706-90-3 Perfluoropentanoic acid 
• 424-36-2 2,2,3,3,4,4,5,5,5-nonafluoropentanoic acid ethyl ester 
• 423-39-2 1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 375-53-1 perfluoropentanal 

Relevant articles and documents

SnX2/Al-promoted formylation of per(poly)fluoroalkyl halides with N,N-dimethylformamide

In the presence of catalytic amounts of stannous salts (20 molpercent) and aluminium powder, per(poly)fluoroalkyl iodides or bromides react smoothly with DMF under mild conditions to give the corresponding per(poly)fluoroalkyl aldehydes in good to excellent yield.A tin-containing intermediate was obtained.A possible mechanism is proposed.

Organofluorine compounds and fluorinating agents part 17: Sonochemical-forced preparation of perfluoroalkanals and their use for non-conventional acetalations of carbohydrates 1, 2

The homologous 1-iodo-perfluoroalkanes 1a-1c and α,ω-dibromo-perfluoroalkanes 4a, 4b were carbonylated with DMF in the presence of Al/SnCl2 or Al/PbBr2 under sonication in a short reaction time. The hydrated aldehydes 2a-2c and 5a, 5b respectively were obtained in good yields allowing dehydration to 3a-3c and 6a, 6b. Some of the fluorinated aldehydes were selected as substrates in a Wittig-Horner olefination assisted by ultrasound and in non-conventional acetalations of methyl α-L-rhamnopyranoside (9). Thus, (E)-1-perfluorooctyl-2-phenylsulphonyl-ethene (8) was prepared from 3c and the phosphonate 7 by Wittig-Horner synthesis. Acetalations of 9 were carried out with the aldehydes (3a, 3b, 6a), hydrated aldehydes (2a, 2b), and the aldehyde hemiacetal 12 respectively, in the presence of dicyclohexylcarbodiimide (DCC). In all cases, a selective epimerization was observed at the C-atom 3 of the monosaccharide, i.e. polyfluoroalkylidenated 6-deoxy-α-L-altropyranosides 10, 11, 13, and 14 were obtained.