355022-17-2

Basic information

• Product Name: 4-(ISOPROPYLAMINO)-3-NITROBENZONITRILE
• Synonyms: 4-(ISOPROPYLAMINO)-3-NITROBENZONITRILE;BUTTPARK 95\04-37
• CAS NO: 355022-17-2
• Molecular Formula: C₁₀H₁₁N₃O₂
• Molecular Weight: 205.21
• Mol File: 355022-17-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 113℃
• Boiling Point: 347.4°C at 760 mmHg
• Flash Point: 163.9°C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 5.4E-05mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-(ISOPROPYLAMINO)-3-NITROBENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(ISOPROPYLAMINO)-3-NITROBENZONITRILE(355022-17-2)
• EPA Substance Registry System: 4-(ISOPROPYLAMINO)-3-NITROBENZONITRILE(355022-17-2)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
• Safety Statements: S36/37:Wear suitable protective clothing and gloves.
• Hazardous Substances Data: 355022-17-2(Hazardous Substances Data)

Usage

General Description

4-(Isopropylamino)-3-nitrobenzonitrile is a chemical compound that consists of a benzene ring with a nitro and cyano group attached to it, as well as an isopropylamino group. It is commonly used in the synthesis of various pharmaceutical and agrochemical compounds. This chemical has a wide range of applications including as an intermediate in the production of drugs, dyes, and other organic compounds. The isopropylamino group provides additional functionality for potential interactions with other compounds, making it useful in drug discovery and development. Additionally, the nitro and cyano groups provide opportunities for further chemical modifications or reactions. Due to its versatility and potential applications, 4-(isopropylamino)-3-nitrobenzonitrile is an important and valuable chemical compound in the field of organic chemistry.

InChI:InChI=1/C10H11N3O2/c1-7(2)12-9-4-3-8(6-11)5-10(9)13(14)15/h3-5,7,12H,1-2H3

Upstream product

• 1009-35-4 4-fluoro-3-nitrobenzonitrile 
• 75-31-0 isopropylamine 
• 939-80-0 4-chloro-3-nitrobenzonitrile 

Downstream Products

• 355022-36-5 4-(5-cyano-1-isopropyl-1H-benzoimidazol-2-yl)-benzoic acid 
• 475490-09-6 2-(4-fluoro-phenyl)-1-isopropyl-1H-benzoimidazole-5-carbonitrile 
• 355022-20-7 4-(isopropylamino)-3-aminobenzonitrile 

Relevant articles and documents

Oxygen-containing five-membered heterocyclic compound, synthesis method, pharmaceutical composition and application

The invention discloses an oxygen-containing five-membered heterocyclic compound, a synthesis method, a pharmaceutical composition and application thereof, and belongs to the technical field of medicines and preparation and application thereof. The oxygen-containing five-membered heterocycle has the biological activity of inhibiting the protein tyrosine phosphatase SHP2, can be used as a tool compound for researching the biological function relevance of the protein tyrosine phosphatase SHP2 in the cell signal transduction process, and provides a new means for preventing and treating cancers and metabolic and immune diseases.

1-Alkyl-benzotriazole-5-carboxylic acids are highly selective agonists of the human orphan G-protein-coupled receptor GPR109b

1-Substituted benzotriazole carboxylic acids have been identified as the first reported examples of selective small-molecule agonists of the human orphan G-protein-coupled receptor GPR109b (HM74), a low-affinity receptor for the HDL-raising drug niacin. N

Synthesis and antimicrobial activity of some new 2-phenyl-N-substituted carboxamido-1H-benzimidazole derivatives

Some 1H-benzimidazole-carboxamide derivatives were prepared and their antimicrobial activities against Staphyloccus aureus, Escherichia coli and Candida albicans evaluated. Compounds 18, 22, and 25 exhibited the best activity against Candida albicans.