355121-64-1Relevant articles and documents
Large scale synthesis of the Cdc42 inhibitor secramine A and its inhibition of cell spreading
Xu, Bo,Pelish, Henry,Kirchhausen, Tomas,Hammond, Gerald B.
, p. 4149 - 4157 (2008/09/19)
We describe a large scale synthesis of secramine A. Consistent with its ability to inhibit activation of the small GTPase Cdc42, we find that secramine A inhibits cell spreading, a process previously shown to be Cdc42-dependent. The Royal Society of Chemistry 2006.
Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product [3]
Pelish,Westwood,Feng,Kirchhausen,Shair
, p. 6740 - 6741 (2007/10/03)
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