35531-57-8

Basic information

• Product Name: 1,3-Dithiane, 2-(3-nitrophenyl)-
• CAS NO: 35531-57-8
• Molecular Formula: C10H11NO2S2
• Molecular Weight: 241.335
• Mol File: 35531-57-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,3-Dithiane, 2-(3-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dithiane, 2-(3-nitrophenyl)-(35531-57-8)
• EPA Substance Registry System: 1,3-Dithiane, 2-(3-nitrophenyl)-(35531-57-8)

Safety Data

• Hazardous Substances Data: 35531-57-8(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 99-61-6 3-nitro-benzaldehyde 
• 109-80-8 1.3-propanedithiol 
• 60171-64-4 3,9-bis-(3-nitro-phenyl)-2,4,8,10-tetraoxa-spiro[5.5]undecane 

Downstream Products

• 99-61-6 3-nitro-benzaldehyde 
• 111997-86-5 2-(3-Nitrophenyl)-1,3-dithian-2-ylium-tribromid 

Relevant articles and documents

A 2 - substituted - 1, 3 - dithiane derivative of the preparation method

The invention provides a preparation method of a 2-substituted-1,3-dithiane derivative. The preparation method comprises the following steps: adding 1,3-dithiane (CAS:505-23-7) and 1,2-dichloroethane (DCE) or dichloromethane (DCM) into a reaction bottle, adding N-chlorosuccinimide (NCS) under ice-bath condition, and stirring for 0.5-1 h to prepare a 2-chloro-1,3-dithiane solution; and adding an aldehyde or ketone compound and a lewis acid catalyst into the above solution, and reacting to prepare the 2-substituted-1,3-dithiane derivative. By using the 1,3-dithiane solid and different types of aldehyde and keto-carbonyl compounds as raw material and using one or more of ferric trichloride, boron trifluoride diethyl etherate, methanesulfonic acid, aluminum trichloride, ferrous chloride and nickel chloride as catalysts, preparation of the 2-substituted-1,3-dithiane derivative is realized. The catalysts used in the invention are cheap and easily available, dosage of the catalysts is low and pollution of the catalysts is little. The solid raw materials used in the invention can avoid use of fetid toxic 1,3-dimercaptopropane with strong volatility, and the purpose of protecting an experimenter's body and reducing environmental pollution is realized. In addition, the preparation method has advantages of mild reaction condition, high yield, simple operation and the like.

New applications of solid silica chloride (SiO2-Cl) in organic synthesis. Efficient preparation of diacetals of 2,2-bis(hydroxymethyl)-1,3-propanediol from different substrates and their transthioacetalization reactions. Efficient regeneration of carbonyl compounds from acetals and acylals

A new application of solid silica chloride, an easily available and efficient catalyst for the preparation of diacetal of 2,2-bis-(hydroxymethyl)-1,3-propanediol from aldehydes, acetals, acylals, and oximes, is described. Transthioacetalization of diacetals of 2,2-bis-(hydroxymethyl)-1,3-propanediol into their corresponding 1,3-dithianes and 1,3-dithiolanes in the presence of silica chloride is presented. Efficient regeneration of carbonyl compounds from their corresponding acetals, ketals, diacetals, and acylals in the presence of this catalyst also is described.