35680-24-1

Basic information

• Product Name: 2-chloro-6-methylpyridin-3-ol
• Synonyms: 2-chloro-6-methylpyridin-3-ol;2-CHLORO-3-HYDROXY-6-PICOLINE;2-Chloro-3-hydroxy-6-methylpyridine
• CAS NO: 35680-24-1
• Molecular Formula: C₆H₆ClNO
• Molecular Weight: 143.57094
• EINECS: 252-675-8
• Product Categories: Pyridine
• Mol File: 35680-24-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 307.3 °C at 760 mmHg
• Flash Point: 139.7 °C
• Appearance: /
• Density: 1.313 g/cm³
• Vapor Pressure: 0.000403mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-chloro-6-methylpyridin-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-6-methylpyridin-3-ol(35680-24-1)
• EPA Substance Registry System: 2-chloro-6-methylpyridin-3-ol(35680-24-1)

Safety Data

• Hazardous Substances Data: 35680-24-1(Hazardous Substances Data)

Usage

Uses

2-Chloro-6-methylpyridin-3-ol is a reagent in the preparation of 1-amino-4-(3-pyridinyloxy)pyridines as ALK5 (activin like kinase 5) inhibitors and anticancer agents.

InChI:InChI=1/C6H6ClNO/c1-4-2-3-5(9)6(7)8-4/h2-3,9H,1H3

Upstream product

• 1121-78-4 5-Hydroxy-2-methylpyridine 

Downstream Products

• 170642-35-0 (S,S)-pseudoephedrine D-β-<6-chloro-5-<(methoxymethyl)oxy>-2-pyridyl>alaninamide 
• 204378-42-7 6-chloro-5-methoxypicoline 
• 1243531-85-2 C₁₉H₂₃ClN₂O₂ 
• 289688-87-5 2-methoxy-6-methylpyridin-3-ol 

Relevant articles and documents

Chemistry and structure elucidation of the kedarcidin chromophore

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PYRIDONE DERIVATIVE HAVING AFFINITY FOR CANNABINOID 2-TYPE RECEPTOR

It was found that the compound having a binding activity to the cannabinoid type 2 receptor represented by the formula (I): wherein R' is a group represented by the formula: -Y1-Y2-Y3Ra wherein Y1 is single bond or the like; Y2 is -C(=O)-NH- or the like; Y3 is optionally substituted aryl or the like; R2 is hydrogen or the like; R3 is alkyl or the like; R4 is alkyl or the like; R5 is optionally substituted alkyl or the like; or R3 and R4 taken together with the adjacent atom form cyclic group or the like.

Iodopropargyl pyridyl and picolinyl ethers and thioethers as paint fungicides

Novel iodopropargyl pyridyl and picolinyl ethers and thioethers are effective antifungal agents. They find special utility in paint for protecting finished paint films from fungal attack.