357209-32-6Relevant articles and documents
Catalytic asymmetric [3+2] annulation of allylsilanes with isatins: Synthesis of spirooxindoles
Hanhan, Nadine V.,Ball-Jones, Nicolas R.,Tran, Ngon T.,Franz, Annaliese K.
supporting information; experimental part, p. 989 - 992 (2012/03/08)
Silyl-inspired spirocycle: The title reaction is the first example of a catalytic asymmetric [3+2] annulation reaction with allylsilanes. The annulation reaction utilizes a chiral ScCl2(SbF6)/L catalyst and TMSCl as a promoter to aff
Kinetic resolution by copper-catalyzed azide-alkyne cycloaddition
Meng, Jun-Cai,Fokin, Valery V.,Finn
, p. 4543 - 4546 (2007/10/03)
The use of chiral pybox ligands imparts enantioselectivity to the Cu I-catalyzed azide-alkyne cycloaddition reaction, in the form of kinetic resolution of α-chiral azides and desymmetrization of gem-diazides. While levels of selectivity are modest, the results show unequivocally that the process benefits from ligand-accelerated catalysis.
Asymmetric ring opening of meso epoxides with TMSCN catalyzed by (pybox)lanthanide complexes.
Schaus,Jacobsen
, p. 1001 - 1004 (2007/10/03)
The asymmetric ring opening of meso epoxides with TMSCN is catalyzed by (pybox)YbCl3 complexes, yielding the beta-trimethylsilyloxy nitrile ring-opened products with good enantioselectivities (83-92% ee). The reaction exhibits a second-order kinetic depen