357401-19-5

Basic information

• Product Name: 3-Bromo-2,6-dimethoxy-4-di(p-methylphenyl)phosphinopyridine
• Synonyms: 3-Bromo-2,6-dimethoxy-4-di(p-methylphenyl)phosphinopyridine
• CAS NO: 357401-19-5
• Molecular Weight: 430.281
• Mol File: 357401-19-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Bromo-2,6-dimethoxy-4-di(p-methylphenyl)phosphinopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-2,6-dimethoxy-4-di(p-methylphenyl)phosphinopyridine(357401-19-5)
• EPA Substance Registry System: 3-Bromo-2,6-dimethoxy-4-di(p-methylphenyl)phosphinopyridine(357401-19-5)

Safety Data

• Hazardous Substances Data: 357401-19-5(Hazardous Substances Data)

Upstream product

• 6231-18-1 2,6-dimethoxypyridine 
• 13445-16-4 3-bromo-2,6-dimethoxypyridine 
• 1019-71-2 chlorodi-p-tolylphosphane 

Downstream Products

• 357401-21-9 4,4'-bis-(di-p-tolyl-phosphinoyl)-2,6,2',6'-tetramethoxy-[3,3']bipyridinyl 
• 357401-20-8 3-bromo-4-(di-p-tolyl-phosphinoyl)-2,6-dimethoxy-pyridine 

Relevant articles and documents

Synthesis and structural characterization of a highly effective chiral dipyridylphosphine ligand and its application in the Ru-catalyzed asymmetric hydrogenation of β-ketoesters

A new chiral dipyridylphosphine ligand Tol-P-Phos has been synthesized and the structure of the complex of (R)-Tol-P-Phos oxide with (-)-dibenzoyl-L-tartaric acid [(-)-DBT] was determined by single crystal X-ray diffraction. The ruthenium complex of Tol-P-Phos, Ru(R-Tol-P-Phos)(C6H6)Cl2, has been found to be a highly active and enantioselective catalyst in the asymmetric hydrogenation of β-ketoesters (up to 98.2% e.e.). The catalyst is also found to be air-stable even in solution.