357425-93-5Relevant articles and documents
Preparation of 1,5-methano-2,3,4,5-tetrahydro-1H-3-benzazepine via Pd-catalyzed cyclization
Singer, Robert A.,McKinley, Jason D.,Barbe, Guillaume,Farlow, Robin A.
, p. 2357 - 2360 (2004)
(Equation Presented) A new approach to prepare 1,5-methano-2,3,4,5- tetrahydro-1H-3-benzanepine (1) is discussed. This strategy utilized a tandem Michael addition and Pd-catalyzed cyclization to afford cyanobenzofulvene acetal 13. This indene intermediate
A general route to the synthesis of 1,5-methano- and 1,5-ethano-2, 3,4,5-tetrahydro-1h-3-benzazepines
O'Donnell, Christopher J.,Singer, Robert A.,Brubaker, Jason D.,McKinley, Jason D.
, p. 5756 - 5759 (2007/10/03)
A general approach to preparing 1,5-methano-(1) and l,5-ethano-2,3,4,5- tetrahydro-lff-3-benzazepine (2) is discussed. This strategy involves converting an indanone or tetralone (4) to a cyanohydrin (3) which is subjected to hydrogenolysis followed by lac
Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic componunds
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, (2008/06/13)
The present invention relates to processes for the preparation of any of the intermediate 1,3-substituted indenes of the formulae (Ia), (Ib) and (Ic) or a mixture thereof: wherein R1, R2, R3, R4, and R5 are defined herein. Compounds of formulae (Ia), (Ib) and (IC) or mixtures thereof are useful in the preparation of compounds of formula (II): wherein R2, R3 and R6 are also defined herein.