35761-09-2Relevant articles and documents
Fridkin et al.
, p. 466,471 (1972)
The small peptide-catalyzed direct asymmetric aldol reaction in water
Dziedzic, Pawel,Zou, Weibiao,Hafren, Jonas,Cordova, Armando
, p. 38 - 40 (2007/10/03)
The asymmetric aldol reaction is a powerful method for forming carbon-carbon bonds. Small peptides with a primary amine as the catalytic residue catalyze asymmetric aqueous aldol reactions between unmodified ketones and aldehydes to furnish the corresponding aldol products with high ees. The high momodularity of the small peptides should enable the construction of several novel catalysts by combinatorial techniques for the aqueous asymmetric aldol reaction. The remarkably high difference in stereoselectivity between the peptide bond-formation was an important step towards the evaluation of asymmetric catalysis and homochilarity.
N,N'-Bis(2-oxo-3-oxazolidinyl)phosphorodiamidic Azide: A Useful Coupling Agent in Peptide Synthesis
Katti, S. B.,Misra, P. K.,Haq, W.,Mathur, K. B.
, p. 3 - 4 (2007/10/02)
N,N'-Bis(2-oxo-3-oxazolidinyl)phosphorodiamidic azide (BOPA), has been developed as an efficient coupling reagent in peptide synthesis.Coupling reaction proceeds smoothly with no detectable racemization.
