35788-21-7

Basic information

• Product Name: adenosine 5'-carboxamide
• Synonyms: adenosine 5'-carboxamide;5'-Amino-5'-oxo-5'-deoxyadenosine;(2S,3S,4R,5R)-5-(6-aMinopurin-9-yl)-3,4-dihydroxyoxolane-2-carboxaMide
• CAS NO: 35788-21-7
• Molecular Formula: C12H22 Co O14
• Molecular Weight: 280.28
• Mol File: 35788-21-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 422.96°C (rough estimate)
• Flash Point: 438.1°C
• Appearance: /
• Density: 1.3705 (rough estimate)
• Vapor Pressure: 4.64E-27mmHg at 25°C
• Refractive Index: 1.7000 (estimate)
• CAS DataBase Reference: adenosine 5'-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: adenosine 5'-carboxamide(35788-21-7)
• EPA Substance Registry System: adenosine 5'-carboxamide(35788-21-7)

Safety Data

• Hazardous Substances Data: 35788-21-7(Hazardous Substances Data)

Usage

General Description

Adenosine 5'-carboxamide, also known as adenosine monophosphate (AMP), is a nucleotide that is composed of adenine, ribose, and a phosphate group. It plays a crucial role in various cellular processes, including energy production and signaling. AMP is a key component in the production of adenosine triphosphate (ATP), the primary energy currency of the cell. It is also involved in the regulation of metabolic pathways and acts as a signaling molecule in numerous cellular processes. Additionally, AMP can be converted into adenosine, a molecule with various physiological roles, including regulating blood flow and promoting sleep and relaxation. Adenosine 5'-carboxamide is thus an important molecule with diverse functions in the body.

InChI:InChI=1/C10H12N6O4/c11-7-3-9(14-1-13-7)16(2-15-3)10-5(18)4(17)6(20-10)8(12)19/h1-2,4-6,10,17-18H,(H2,12,19)(H2,11,13,14)/t4-,5+,6-,10+/m0/s1

Upstream product

• 39491-49-1 2',3'-O-isopropylideneadenosine-5'-carbonyl chloride 
• 28440-13-3 (3aS,4S,6R,6aR)-2,2-dimethyl-6-(6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuro[3,4-d][1,3]dioxole-4-carboxylic acid 
• 879367-53-0 (3aS,4S,6R,6aR)-6-(6-Chloro-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid amide 
• 104940-65-0 1'-deoxy-1'-(6-chloro-9H-purin-9-yl)2',3'-O-isopropylidene-β-D-ribofuranosyl chloride 
• 2140-11-6 2',3'-O-isopropylideneinosine 
• 23754-29-2 2',3'-O-isopropylideneadenosine-5'-carboxylic acid methyl ester 
• 19234-66-3 2',3'-isopropylideneadenosine-5'-carboxylic acid 
• 35788-22-8 2',3'-O-isopropylideneadenosine-5'-carboxamide 
• 159647-45-7 (3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid 4-nitro-phenyl ester 

Relevant articles and documents

Inactivation of S-adenosyl-L-homocysteine hydrolase by amide and ester derivatives of adenosine-5'-carboxylic acid

S-Adenosyl-L-homocysteine (AdoHcy) hydrolase has been shown to have (576') hydrolytic activity with vinyl (5') or homovinyl (6') halides derived from adenosine (Ado). This hydrolyric activity is independent of its 3'- oxidative activity. The vinyl (or hom

N6-substituted N-alkyladenosine-5'-uronamides: bifunctional ligands having recognition groups for A1 and A2 adenosine receptors.

The coronary vasoactivity of N-ethyl-1'-deoxy-1'-(6-amino-9H-purin-9-yl)-beta-D-ribofuranuronamide (NECA, 1) is over 2 orders of magnitude greater than that of adenosine, and the vasoactivity of certain N6-substituted adenosines is as much as 1 order of m

Adenosine-5'-carboxylic acid amides

Adenosine-5'-carboxylic acid amides represented by the formula STR1 wherein R1 and R2 are each selected from the group consisting of hydrogen, loweralkyl, lowerhaloalkyl, lowerhydroxyalkyl, lowercycloalkyl, loweralkylcycloalkyl, loweralkenyl, lowerhaloalkenyl, lowerhydroxyalkenyl, loweralkynyl, lowerhaloalkynyl, benzylamino, phenyl, loweralkylphenyl, loweralkoxyloweralkyl, substituted phenyl, 2-methylfuran or di(C1 -C4)alkylamino(C1 -C4)alkyl, adamantyl or R1 and R2 taken together form a 5 or 6 membered heterocyclic moiety; R3 and R4 are hydrogen or acyl, or taken together form an isopropylidene or a benzylidene group; or a pharmaceutically acceptable acid addition salt thereof.